Results 111 to 120 of about 106,695 (313)

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Transgenic zero-erucic and high-oleic mustard oil improves glucose clearance rate, erythrocyte membrane docosahexaenoic acid content and reduces osmotic fragility of erythrocytes in male Syrian golden hamsters

Journal of Nutrition & Intermediary Metabolism, 2018
Brassica juncea, the Indian mustard variety has high erucic acid (22:1 n-9) in its oil, which causes several deleterious effects. The Centre for Genetic Manipulation of Crop Plants (India) has developed a zero-erucic and high-oleic acid transgenic ...
Anantha Krishna Vemuri, Vani Acharya, Lakshmi Rajkumar Ponday, Shanmugam Murugaiha Jeyakumar, Ayyalasomayajula Vajreswari   +4 more
doaj   +1 more source

Local Deformation of the Erythrocyte Membrane [PDF]

, 2005
A rapid local deformation of the erythrocyte membrane in the shape of an imprint caused by illumination with a focused laser beam in the presence of an external fluorophore has been investigated.
Wong, Felix
core  

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Alteration in Membrane Protein, Antioxidant Status and Hexokinase Activity in Erythrocytes of Ccl4- Induced Cirrhotic Rats

Acta Medica Iranica, 2014
Several studies have shown that hepatocyte membrane composition changes in patients with cholestasis and cirrhosis. These alterations that are because of intracellular oxidative stress are supposed to be reflected in erythrocyte membrane. The aim of this
Amir Hossein Doustimotlagh, Ahmad Reza Dehpour, Mitra Nourbakhsh, Abolfazl Golestani   +3 more
doaj  

Erythrocyte membrane-coated NIR-triggered biomimetic nanovectors with programmed delivery for photodynamic therapy of cancer

, 2015
A new type of photodynamic therapy (PDT) agents using upconversion nanoparticles (UCNPs) with incorporated photosensitizers as the inner core and an erythrocyte membrane (RM) decorated with dual targeting moieties as the cloak is developed.
Lv, Yanlin, Wei, Wei, Ni, Dezhi, Ma, Guanghui, Tian, Zhiyuan, Ding, Hui, Wang, Jie   +6 more
core   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Avaliação das esterases sanguíneas na doença de Alzheimer.

Acta Médica Portuguesa, 1992
The aim of this work was to evaluate a possible correlation between erythrocyte acetylcholinesterase activity (AChE) and membrane fluidity expressed by fluorescence polarization of--1,6--diphenyl 1,3,5--hexatriene (DPH).
C Saldanha, T Quintão, C Garcia
doaj   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

The effects of dyslipidaemia and cholesterol modulation on erythrocyte susceptibility to malaria parasite infection

Malaria Journal, 2019
Background Malaria disease commences when blood-stage parasites, called merozoites, invade human erythrocytes. Whilst the process of invasion is traditionally seen as being entirely merozoite-driven, emerging data suggests erythrocyte biophysical ...
Marion Koch, Jaimini Cegla, Ben Jones, Yuning Lu, Ziad Mallat, Andrew M. Blagborough, Fiona Angrisano, Jake Baum   +7 more
doaj   +1 more source