Results 181 to 190 of about 170,191 (305)

Acute and Subacute Toxicity Evaluation of Erythrocyte Membrane-Coated Boron Nitride Nanoparticles. [PDF]

J Funct Biomater, 2023
He J, Zhang X, Liu L, Wang Y, Liu R, Li M, Gao F.   +6 more
europepmc   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Erythrocyte membrane lipid profile in children and adolescents with metabolic dysfunction-associated steatotic liver disease and insulin resistance: a preliminary study. [PDF]

Sci Rep
Zdanowicz K, Harasim-Symbor E, Sienkiewicz K, Wojtkowska M, Janica J, Flisiak-Jackiewicz M, Bobrus-Chociej A, Chabowski A, Lebensztejn DM.   +8 more
europepmc   +1 more source

The Role of Erythrocyte Membrane Protein Band 4.1-like 3 in Idiopathic Pulmonary Fibrosis. [PDF]

Int J Mol Sci, 2023
Kim MK, Lee JU, Lee SJ, Chang HS, Park JS, Park CS.   +5 more
europepmc   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Biosynthesis of selenium nanoparticles from Dahlia pinnata tuberous roots with antibacterial, antidiabetic, and erythrocyte membrane protective activities. [PDF]

Sci Rep
Mekky AE, Abdo AM, Haggag MI, Elhaw MH, Kadry MM, Ghanem SM, Salama MM, Soliman AM, Mahmoud NN.   +8 more
europepmc   +1 more source

Tumor-Targeted Erythrocyte Membrane Nanoparticles for Theranostics of Triple-Negative Breast Cancer. [PDF]

Pharmaceutics, 2023
Choi MJ, Lee YK, Choi KC, Lee DH, Jeong HY, Kang SJ, Kim MW, You YM, Im CS, Lee TS, Park YS.   +10 more
europepmc   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Impaired lipid homeostasis and elevated lipid oxidation of erythrocyte membrane in adolescent depression. [PDF]

Redox Biol
Wang J, Hu X, Li Y, Li S, Wang T, Wang D, Gao Y, Wang Q, Zhou J, Wan C.   +9 more
europepmc   +1 more source

Eriocitrin Disrupts Erythrocyte Membrane Asymmetry through Oxidative Stress and Calcium Signaling and the Activation of Casein Kinase 1α and Rac1 GTPase. [PDF]

Pharmaceuticals (Basel), 2023
Alghareeb SA, Alsughayyir J, Alfhili MA.
europepmc   +1 more source