Results 101 to 110 of about 60,840 (277)

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

open access: yesInterdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li   +24 more
wiley   +1 more source

Study of erythrocyte sedimentation in human blood through the photoacoustic signals analysis

open access: yesPhotoacoustics
Introduction: In this study, we utilized the pulsed photoacoustic (PA) technique to analyze globular sedimentation in whole human blood, with a focus on distinguishing between healthy individuals and those with hemolytic anemia.
Argelia Pérez-Pacheco   +8 more
doaj   +1 more source

Asprosin as a Potential Link Between Vascular Inflammation and Disease Activity in Behçet's Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Serum asprosin levels are significantly elevated in patients with Behçet's disease compared to healthy controls. Asprosin concentrations increase progressively with disease activity and are strongly associated with vascular involvement and uveitis, suggesting a potential role as a biomarker of vascular inflammation and disease severity.
Zeynep Kaya   +6 more
wiley   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

open access: yesJournal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva   +4 more
wiley   +1 more source

The erythrocyte sedimentation rate time curve: critique of an established solution.

open access: yes, 1983
A sigmoid curve is required to characterize the time course of the erythrocyte sedimentation rate (ESR) test. The widely used 'logistic' form has been thought to have a theoretical foundation in a sedimentation model of Puccini et al. (1977) which claims
Dorrington, Keith   +2 more
core   +1 more source

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The increasing incidence of inflammatory bowel disease (IBD) in paediatric populations underscores the importance of effective management strategies. Anti–tumor necrosis factor (anti‐TNF) agents, such as infliximab (IFX) and adalimumab (ADL), are key treatments for inducing and maintaining remission in IBD, but many patients ...
Karlotta Pauline Hubert   +2 more
wiley   +1 more source

Upper and small bowel Crohn's disease in Brazilian children: Phenotypic characteristic and surgical risk

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Upper and small bowel Crohn's disease (U‐SBCD) represents a clinically aggressive phenotype with high complication rates yet remains diagnostically challenging. In low‐ and middle‐income countries (LMICs), limited inflammatory bowel disease (IBD) awareness contributes to diagnostic delays, but their impact on U‐SBCD outcomes remains
Jane Oba   +12 more
wiley   +1 more source

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