Results 171 to 180 of about 60,840 (277)

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, Volume 78, Issue 6, Page 696-702, June 2026.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, Volume 13, Issue 33, 15 June 2026.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1327-1338, June 2026.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Neonatal Wet Gangrene With Early Auto‐Amputation in a Resource‐Limited Setting With Incomplete Etiologic Workup: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Neonatal limb gangrene with auto‐amputation is rare and often idiopathic. Early recognition, prompt referral, and thorough etiologic workup—despite resource limitations—are critical. Wet gangrene requires broad‐spectrum antibiotics, wound care, and timely surgical amputation to preserve growth plates and allow future prosthesis fitting.
Milki Tufa Feyisa, Beza Eshetu, Tolosa Dibisa, Mulatu Gshaw, Birhanu Tolera, Endalew Dessie Birara, Adugna Lamessa, Tamirat Godebo Woyimo   +7 more
wiley   +1 more source

ERDHEIM‐Chester Disease: Two Fatal Cases With Unusual Presentations

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Fluorodeoxyglucose positron emission tomography‐computed tomography (FDG PET‐CT) demonstrated markedly increased metabolic activity in serosal surfaces including pericardium, pleura, and renal fascia, as well as diffuse uptake along vascular walls, particularly the entire aorta.
Ribero‐Vargas Daniel Andres, C. Álvarez Payares José, Murillo‐Pérez Juliana   +2 more
wiley   +1 more source

Clinical significance of erythrocyte sedimentation rate-based stratification in a large retrospective SLE cohort. [PDF]

Front Immunol
Wang F, Xu Y, Zhang W, Pan W, Liu L, Wu M, Ding F, Hu H, Ding X, Wei H, Zou Y, Kong W, Zhu Y, Feng X, Sun L.   +14 more
europepmc   +1 more source

Guillain‐Barré Syndrome Following Herpes Zoster Ophthalmicus: A Rare Case of Acute Motor Axonal Neuropathy

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Herpes zoster ophthalmicus (HZO) refers to reactivation of varicella–zoster virus involving the ophthalmic division of the trigeminal nerve. Guillain‐Barré syndrome (GBS) has been infrequently reported following herpes zoster infection, and its occurrence after HZO is particularly uncommon.
Asad Ullah Khan, Moeez Ahmad Saeed, Ali Azmat, Rehman Khan, Nadeem Yousaf, Talha Khalid, Kashaf Imtiaz, Ali Gohar, Muhammad Husnain Ahmad   +8 more
wiley   +1 more source

Does Anemia Independently Influence the Erythrocyte Sedimentation Rate in Rheumatoid Arthritis? A Multivariate Analysis From North India. [PDF]

Cureus
Jindal A, Kaur K, Goel A, Setia P, Lanjewar S.   +4 more
europepmc   +1 more source

A Case Report on Meningitis Complicated by Acute Ischemic Stroke and Failed Thrombolysis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Ischemic stroke is one of the rare but grave complications of meningitis with poor outcomes and long‐term sequelae, and the role of thrombolysis with infection‐related stroke remains uncertain. This case report documents a 52‐year‐old man presented with fever, headache, vomiting, and altered sensorium, and on examination he had neck rigidity ...
Sonam Dema, Dechen Choden, Sonam Wangmo
wiley   +1 more source