Results 211 to 220 of about 115,240 (299)

XIAP Deficiency Impairs Colonic Tuft Cell Development and Predisposes to Crohn's Disease

open access: yesMedComm, Volume 7, Issue 5, May 2026.
XIAP deficiency leads to impaired colonic tuft cells development and JAK–‐STAT pathway hyperactivation in CD patients and mice. Mechanically, XIAP regulates tuft cells development through Wnt–‐TLE4/TCF–‐ASCL2 signaling. Tuft cells deficiency predisposes XIAP‑‐deficient CD patients or Xiap−/−‐/‐ mice to hazardous microbial effects, driving colonic ...
Rongli Fang   +28 more
wiley   +1 more source

Multidisciplinary Approach to Complex Lower Extremity Limb Salvage in Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome: A Case Report

open access: yesMicrosurgery, Volume 46, Issue 4, May 2026.
ABSTRACT Limb salvage using free tissue transfer in patients with rare autoinflammatory syndromes is poorly described, and the safety of microvascular reconstruction in this population remains uncertain. Hereditary pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is characterized by dysregulated inflammation, pathergy, and impaired ...
Michael M. Talanker   +9 more
wiley   +1 more source

Prognostic Significance of Erythrocyte Sedimentation Rate for Survival in Equine Colic. [PDF]

open access: yesAnimals (Basel)
Meistro F   +9 more
europepmc   +1 more source

Estimating Vascular Age to Evaluate the Association Between Aging and Cardiovascular Disease

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
The normalized cardiovascular age acceleration (NCAA) index is estimated using the Klemera‐Doubal method (KDM) based on annual physical examination records at Tongji Hospital in Wuhan, China. Vascular function‐based (basic) NCAA shows different associations with cardiometabolic risk factors by age and sex.
Yueqi Lu   +10 more
wiley   +1 more source

Risk factors for impaired surgical wound healing after spinal tuberculosis surgery: a retrospective comparative trial. [PDF]

open access: yesFront Surg
Xiaonan W   +8 more
europepmc   +1 more source

Medium‐term pulmonary outcomes (<6 months) after pediatric COVID‐19 infection evaluated using impulse oscillometry and spirometry

open access: yesPediatric Allergy and Immunology, Volume 37, Issue 5, May 2026.
Abstract Objective Although coronavirus disease 2019 (COVID‐19) usually exhibits a mild clinical course in children, concerns remain regarding persistent airway dysfunction after recovery. This study aimed to evaluate pulmonary function tests (PFTs) in children following mild COVID‐19 infection and to compare the findings with those of healthy controls.
Simge Atar Bese   +6 more
wiley   +1 more source

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