Results 231 to 240 of about 78,012 (285)

Single-cell sequencing reveals cellular differences and potential mechanisms in congenital pulmonary airway malformation. [PDF]

Front Med (Lausanne)
Huang J, Chen Q, Hong S, Hong J, Cao H.
europepmc   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Clinical Characteristics and Disease Course of Livedoid Vasculopathy: A 10-Year Retrospective Analysis. [PDF]

Clin Cosmet Investig Dermatol
Gao Y, Li Y, Mairepati D, Wu H, Liu J, Han J, Zhou H.   +6 more
europepmc   +1 more source

Cholesterol Metabolism Regulated Nanoliposome Ameliorates Chemo/Photothermal Therapy Reversing CD8+ T Cell Exhaustion

Exploration, EarlyView.
Our work addresses the challenge of treating triple‐negative breast cancer by developing a multifunctional nanoliposome, ictLipo. The goal was to enhance antitumor immunity by combining photothermal therapy and chemotherapy while simultaneously tackling two major roadblocks: immunosuppression from cholesterol in the tumor microenvironment and therapy ...
Panpan Xue, Tingjie Bai, Huilan Zhuang, Angelo H. All, Shuangqian Yan, Xuemei Zeng   +5 more
wiley   +1 more source

Genetic biomarkers and crucial cell subsets of iron metabolism in Beta-Thalassemia: insights from bioinformatics and experimental validation. [PDF]

Ann Hematol
Wei R, Qiu D, Zeng X.
europepmc   +1 more source

Phase‐Change Assembling Nanostructures Synergistically Potentiate Tumor Radiosensitivity by Reducing the Stemness of Cancer Stem‐Like Cells

Exploration, EarlyView.
A eutectic phase‐change mixture of natural fatty acids was introduced to serve as a gating material for the near‐infrared‐triggered precise release of oxygen and nitroimidazole radiosensitizer in tumors. The stemness of cancer stem‐like cells was shown to be significantly reduced through the delivery of oxygen to deep tumors.
Yuanfang Chen, Xueyin Hu, Ze Hu, Yuwei Yang, Changfen Bi, Guangyou Shi, Lumeng Zhang, Wenqing Xu, Shuqin Li, Luntao Liu   +9 more
wiley   +1 more source

Glial <i>betaPix</i> is essential for blood vessel development in the zebrafish brain. [PDF]

Elife
Chiu S, Zhou Q, Xiao C, Bai L, Zhu X, Ding W, Xiong JW.   +6 more
europepmc   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

Food Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo, Jethro Roland Misse Ngangue Ekwala, Somon Régine Tuem, Stéphano Tene Tambo, Merlin Ngafon Nchoutpouen, Valery Jean François Nsoga, Jules Christophe Koule Manz, Jordan Mekui Nwotue, Mathieu Ndomou   +8 more
wiley   +1 more source

Clinical and Genetic Analysis of Dehydrated Hereditary Stomatocytosis: A Case Report. [PDF]

Clin Case Rep
Ming C, Wu S, Pan R.
europepmc   +1 more source