Oxidative stress in the pathogenesis of systemic scleroderma: An overview [PDF]
, 2018 Systemic sclerosis (SSc) is a rare disorder of the connective tissue characterized by fibrosis of the skin, skeletal muscles and visceral organs. Additional manifestations include activation of the immune system and vascular injury. SSc causes disability
Gambardella, Lucrezia +5 more
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Abnormalities of the Erythrocyte Membrane [PDF]
Pediatric Clinics of North America, 2013 Primary abnormalities of the erythrocyte membrane are characterized by clinical, laboratory, and genetic heterogeneity. Among this group, hereditary spherocytosis patients are more likely to experience symptomatic anemia. Treatment of hereditary spherocytosis with splenectomy is curative in most patients.
openaire +2 more sources
Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]
, 2018 The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky +3 more
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Abnormal phospholipid molecular species of erythrocytes in sickle cell anemia
Journal of Lipid Research, 1997 As the lipid composition of cell membranes has significant effects upon cellular function, we hypothesized that the membranes of sickle cells might have a distorted lipid composition.
W E Connor +5 more
doaj +1 more source
Sickle Cell Anaemia with Antiglobulin Positive Autoimmune Haemolytic Crisis [PDF]
Journal of Clinical and Diagnostic Research, 2023 Dear Editor, Immune-mediated haemolytic crises can worsen congenital anemias, and although autoantibodies have been identified, they are not frequently associated with overt Autoimmune Haemolytic Anaemia (AIHA) [1].
Saniya Khan +3 more
doaj +1 more source
Abnormal Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus
Сахарный диабет, 2009 Aim. To measure Na-K-ATPase activity in erythrocytes from patients with diabetes mellitus (DM), elucidate its relationship with clinical manifestationsof the disease and biochemical blood characteristics. Materials and methods.
Z M Shamansurova +5 more
doaj +1 more source
Platelet-Induced Clumping of Plasmodium falciparum–Infected Erythrocytes from Malawian Patients with Cerebral Malaria—Possible Modulation In Vivo by Thrombocytopenia [PDF]
, 2008 Platelets may play a role in the pathogenesis of human cerebral malaria (CM), and they have been shown to induce clumping of Plasmodium falciparum–parasitized red blood cells (PRBCs) in vitro.
Barnwell JW +18 more
core +1 more source
Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
, 2020 Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core +1 more source
Copper-transporting ATPase is important for malaria parasite fertility [PDF]
, 2013 Homeostasis of the trace element copper is essential to all eukaryotic life. Copper serves as a cofactor in metalloenzymes and catalyses electron transfer reactions as well as the generation of potentially toxic reactive oxygen species. Here, we describe
Kenthirapalan, Sanketha +3 more
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Supplementation of iron alone and combined with vitamins improves haematological status, erythrocyte membrane fluidity and oxidative stress in anaemic pregnant women [PDF]
, 2010 Pregnancy is a condition exhibiting increased susceptibility to oxidative stress, and Fe plays a central role in generating harmful oxygen species. The objective of the present study is to investigate the changes in haematological status, oxidative ...
Aiguo, M. +7 more
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