Results 61 to 70 of about 1,920,566 (255)

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

open access: yesPLoS ONE, 2007
A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced ...
Federica Verra   +14 more
doaj   +1 more source

Impending anterior ischemic optic neuropathy with elements of retinal vein occlusion in a patient on interferon for polycythemia vera. [PDF]

open access: yes, 2012
We describe the course and likely pathophysiology of impending anterior ischemic optic neuropathy (AION) and retinal vein occlusion in a 56-year-old man with polycythemia vera managed with interferon alpha for 2 years.
Hirsch, Louis K   +2 more
core   +1 more source

Phosphorylation in erythrocyte membranes from abnormally shaped cells [PDF]

open access: yesBlood, 1976
Erythrocyte protein phosphorylation was examined in membrane preparations of 25 patients with hereditary spherocytosis (HS). Reduced phosphorylation in substrate polypeptides was observed in 22 HS erythrocyte membranes for both splenectomized and nonsplenectomized patients.
A C, Greenquist, S B, Shohet
openaire   +3 more sources

Study on impacts of direct supplementation of choline into semi-intensive fish culture system based on haematopoietic alterations

open access: yesEnvironmental and Sustainability Indicators, 2021
The present study investigated the impact of choline chloride at the dose of 350 ​g bigha−1 fortnightly for 90 days culture on Indian Major Carps (IMCs) (Labeo rohita, Catla catla) and Air-breathing fishes (Clarias batracus and Anabas testudineus) in ...
Subhas Das   +7 more
doaj   +1 more source

Erythrocyte volume distribution in normal and abnormal subjects [PDF]

open access: yesBlood, 1975
Size-frequency distribution curves of erythrocytes were generated with the Coulter Counter in 73 normal subjects and patients. Mean corpuscular volume (MCV) determined by routine calculation and MCV determined by size-frequency distribution were similar in all normal subjects and in patients with a single population of erythrocytes.
J D, Bessman, R K, Johnson
openaire   +3 more sources

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Erythrocyte membrane skeleton abnormalities in severe beta-thalassemia [PDF]

open access: yesBlood, 1987
The protein composition of ghosts, inside-out vesicles (IOV), and membrane skeletons (MS) of erythrocytes (RBC) from splenectomized (spx) and nonsplenectomized (non-spx) patients with beta-thalassemia major and beta-thalassemia intermedia was determined. Ghosts from spx thalassemia intermedia patients had a significant increase in their globin content (
E, Shinar   +3 more
openaire   +3 more sources

Abnormal phosphoenolpyruvate transport in erythrocytes of hereditary spherocytosis [PDF]

open access: yesBlood, 1981
Abstract The rate of phosphoenolpyruvate transport in erythrocytes from patients with hereditary spherocytosis and from healthy individuals was examined in a 0.1 M citrate buffer (pH 6.1 at 37 degrees C) containing 10 mM phosphoenolpyruvate and 10 mM NaF. The rate in erythrocytes from patients with hereditary spherocytosis was 0.09 +/- 0.
H, Ideguchi, N, Hamasaki, Y, Ikehara
openaire   +4 more sources

TSH Receptor Reduces Hemoglobin S Polymerization and Increases Deformability and Adhesion of Sickle Erythrocytes

open access: yesAnemia
SCD is a hereditary disorder caused by genetic mutation in the beta-globin gene, resulting in abnormal hemoglobin, HbS that forms sickle-shaped erythrocytes under hypoxia.
Evelyn Mendonça-Reis   +4 more
doaj   +1 more source

Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]

open access: yes, 2014
ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W   +6 more
core   +2 more sources

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