Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial
Journal of the European Academy of Dermatology and Venereology, EarlyView.This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami +6 more
wiley +1 more source
Subacute cutaneous lupus erythematosus presenting as erythroderma
Indian Journal of Dermatology, 2014 Subacute cutaneous lupus erythematosus (SCLE) is a type of lupus erythematosus having distinct characteristic clinical, serologic, and genetic features. Other than the commonly occurring papulosquamous and annular polycyclic lesion, rarely it may present
Varadraj V Pai +5 more
doaj +1 more source
I Jornada de expertos en ictiosis [PDF]
, 2013 On June 22, 2012 the First Symposium of Ichthyosis Experts in Spain was held at the Hospital Niño de Jesús in Madrid. It was a one-day symposium for dermatologists, pediatricians, and physicians-in-training interested in this disease, as well as for ...
A. Hernández-Martín +10 more
core +3 more sources
Bullae and Scales in a Newborn
JEADV Clinical Practice, EarlyView.
Hamad El Hajj +3 more
wiley +1 more source
Dermatology 2.0: Precision medicine for inflammatory skin diseases
Journal of the European Academy of Dermatology and Venereology, EarlyView.Digital immune mapping of transcriptomics profiles from inflammatory skin disease biopsies enables precise molecular diagnosis, quantification of immune modules and personalized therapy selection by matching dominant immune signatures to targeted treatments.
Jeremy Di Domizio +4 more
wiley +1 more source
Erythrodermic Psoriasis with Superimposed Fungal Infection-a Presentation in the Emergency Room
Eurasian Journal of Emergency Medicine, 2018 Erythrodermic psoriasis or erythroderma is a life-threatening, generalized exfoliative dermatitis involving majority of the body surface. A detailed evaluation is required for the identification of its underlying cause to successfully treat and prevent ...
Muhammad Akbar Baig, Sadaf Sheikh
doaj +1 more source
Sezary Syndrome presenting with leonine facies and treated with low-dose subcutaneous alemtuzumab [PDF]
, 2012 Cutaneous T-cell lymphomas (CTCL) comprise a group of diseases characterized by the accumulation of malignant T cells within the skin. Sezary syndrome represents an aggressive form of CTCL, in which the skin is diffusely affected and the peripheral blood
Alves, R. +4 more
core
The phenotypic and genotypic spectra of ichthyosis with confetti plus novel genetic variation in the 3' end of KRT10: from disease to a syndrome [PDF]
, 2015 Ichthyosis with confetti (IWC) is a genodermatosis caused by dominant negative mutations in the gene encoding keratin 10 (KRT10). We investigated clinical and genetic details of a substantial number of patients with IWC in order to define major and minor
Brena, Michela +7 more
core +1 more source
Dupilumab Reduces Pruritus in Twins With Sjögren–Larsson Syndrome
Pediatric Dermatology, EarlyView.ABSTRACT Sjögren–Larsson Syndrome (SLS), now termed ALDH3A2‐syndromic epidermal differentiation disorder (sEDD), is a rare genetic disorder marked by thickened skin, spasticity, and intellectual disability. Intractable pruritus is a nearly universal and debilitating feature of SLS that remains poorly managed by current therapies. We describe 4‐year‐old
Kennedy Gallagher +3 more
wiley +1 more source
Review of common cutaneous adverse drug reactions
South African Family Practice, 2005 No abstract available.
M.H. Motswaledi
doaj +1 more source