Results 81 to 90 of about 12,152 (258)
Pediatric Dermatology, EarlyView.ABSTRACT Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9‐year‐old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL‐17A inhibitor, following initial therapeutic resistance to topical ...
Zeno Fratton +2 more
wiley +1 more source
Phase II evaluation of VDC-1101 in canine cutaneous T-cell lymphoma. [PDF]
, 2014 BackgroundCanine cutaneous T-cell lymphoma (CTCL) is an uncommon disease for which efficacious therapies are lacking. The novel anticancer nucleotide prodrug VDC-1101 (formerly known as GS-9219) has shown efficacy in dogs with multicentric lymphoma.
Burgess, KE +5 more
core +2 more sources
Pediatric Dermatology, EarlyView.ABSTRACT Keratitis–ichthyosis–deafness (KID) syndrome is a rare genetic condition typically presenting at birth with ichthyosiform erythroderma and bilateral hearing loss and later progressing to diffuse keratodermatous plaques with scaling. The condition is associated with mutations in the GJB2 gene, which lead to aberrant activation of connexin ...
Radhika Gupta +3 more
wiley +1 more source
Indian Journal of Dermatology, 2015 Lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely. A 40 year old female patient presented with a 1 year history of developing multiple,
Neema M Ali, Ramesh Bhat, Shwetha B Rao
doaj +1 more source
Dupilumab Reduces Pruritus in Twins With Sjögren–Larsson Syndrome
Pediatric Dermatology, EarlyView.ABSTRACT Sjögren–Larsson Syndrome (SLS), now termed ALDH3A2‐syndromic epidermal differentiation disorder (sEDD), is a rare genetic disorder marked by thickened skin, spasticity, and intellectual disability. Intractable pruritus is a nearly universal and debilitating feature of SLS that remains poorly managed by current therapies. We describe 4‐year‐old
Kennedy Gallagher +3 more
wiley +1 more source
Neonatal erythroderma: Diagnostic and therapeutic challenges
Indian Journal of Dermatology, 2012 Erythroderma a life-threatening entity during the fi rst one month, and many a time, a manifestation of genodermatosis, immune defi ciency, psoriasis, metabolic diseases, and infections.
Sandipan Dhar +2 more
doaj +1 more source
A mutational hot spot in keratin 10 (KRT 10) in patients with epidermolytic hyperkeratosis [PDF]
, 2017 Epidermolytic hyperkeratosis (EHK), (bullous congenital ichthyosiform erythroderma), is an autosomal dominant human skin disorder. Recently, we and others have described mutations in keratins 1 and 10 (K1 and K10) in patients with this disease. Structure-
Anton-Lamprecht, Ingrun +7 more
core
American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero +17 more
wiley +1 more source
A 53-Year-Old Woman with Persistent Erythroderma and Dyspnea
Case Reports in Clinical Practice, 2016 A 53-year-old obese woman with history of obsessive compulsive disorder was referred to the general internal medicine clinic because of erythroderma and progressive dyspnea. Tapering psychiatric drugs and administering corticosteroids did not help her. A
Maryam Edalatifard +3 more
doaj