Results 1 to 10 of about 3,693 (191)

Patient-Oriented Priorities for Pediatric Erythromelalgia: A Priority-Setting Process [PDF]

Children
Background/Objectives: Erythromelalgia is a rare condition characterized by burning pain, redness, and warmth primarily in the extremities, usually worsened by heat and alleviated by cold. The objective of this study was to identify the top 10 priorities
Don Daniel Ocay, Meghan Halpin, Ella Ford, Karen Keighley, Neva Keighley, Nikki Ramsay, Tayla Ramsay, Camelia M. Sheridan, Sarah M. Sheridan, Kirsten R. Tice, Deirdre De Ranieri, See Wan Tham, Catherine A. Brownstein, Jacqui Clinch, Dawn Marie Davis, Carolina Donado, Genevieve D’Souza, Deepa Kattail, Kimberly Lobo, Danielle Ravetti, Paola Sandroni, Jennifer N. Stinson, Gary A. Walco, Suellen M. Walker, Timothy W. Yu, Charles B. Berde   +25 more
doaj   +2 more sources

Genetic Variants in the SCN9A Gene are Detected in a Minority of Erythromelalgia Patients [PDF]

Acta Dermato-Venereologica
Gain-of-function variants in the voltage-gated sodium channel Nav1.7, encoded by the SCN9A gene, have previously been identified in patients with erythromelalgia, a clinical diagnosis defined by intermittent attacks of painful, hot, swollen, and red skin,
Mari Skystad Kvernebo, Celene Grayson, Ioannis M. Stylianou, Virginia Woloshen, Christopher Radomski, Cato Mørk, Knut Kvernebo   +6 more
doaj   +2 more sources

Mepyramine targets mutant Nav1.7 channels to relieve pain and erythema in primary erythromelalgia patients [PDF]

Frontiers in Medicine
Gain-of-function mutations in SCN9A, which encodes the Nav1.7 voltage-gated sodium channel, are known to cause primary erythromelalgia (PEM). This condition is characterized by recurrent episodes of erythema, burning pain, and warmth in the extremities ...
Myriam Ducrocq, Myriam Ducrocq, Virginie Penalba, Virginie Penalba, Laura Castillo, Laura Castillo, Christine Bodemer, Céline Greco, Patrick Delmas, Patrick Delmas   +9 more
doaj   +2 more sources

Comparative Efficacy and Tolerability of Treatments for Erythromelalgia: A Systematic Review [PDF]

Medicina
Background and Objectives: Erythromelalgia (EM) is an uncommon condition marked by recurring redness, intense burning sensations, and elevated limb warmth.
Abdullah S. Algarni, Reem M. Alharthi, Shaden O. Alqurashi, Ruba M. Alghanmi, Rimaz R. Aldawsari, Maysaa A. Alghamdi, Ramy Samargandi   +6 more
doaj   +2 more sources

A case of erythromelalgia with gastrointestinal dysautonomia treated with immunoglobulin: A case report [PDF]

SAGE Open Medical Case Reports, 2023
An 18-year-old female with a history of atopic march, hyperhidrosis, and eosinophilic esophagitis was diagnosed with erythromelalgia and gastrointestinal dysautonomia secondary to presumed autoimmune small fiber neuropathy.
Adrienn N Bourkas, Ryan Geng, Matthew Sibbald, R Gary Sibbald   +3 more
doaj   +2 more sources

Intravenous immunoglobulin therapy in erythromelalgia management: a case report [PDF]

Einstein (São Paulo)
A 49-year-old woman presented with a 16-year history of burning pain, warmth, redness, and edema in both toes, feet, legs and calves. Despite extensive medical testing, including genetic analysis, no specific cause was identified.
Renato Ádler Pomilio de Sousa, Luydson Richardson Silva Vasconcelos, Marcus Villander Barros de Oliveira Sá   +2 more
doaj   +2 more sources

Essential Thrombocytosis in a Postmenopausal Female a Rare Cause of Aquagenic Pruritus [PDF]

Journal of Mid-Life Health
Essential thrombocytosis (ET) is a hematopoietic stem cell disorder in which the overproduction of platelets without a definable cause occurs. Its incidence is 1–2 per 100,000 population with female preponderance.
Prabhat Agrawal, Ruchika Garg, Shiv Sagar Yadav, Sandipta Panda   +3 more
doaj   +2 more sources

Erythromelalgia [PDF]

Mayo Clinic Proceedings, 2004
Erythromelalgia (EM) is a rare poorly understood clinical condition that is characterized by intense burning pain, pronounced erythema, and increased skin temperature. Although there are many classifications of the disease, it can basically be divided into primary which begins spontaneously at any age, and secondary, which is associated with ...
Ljubojević, Suzana, Lipozenčić, Jasna, Pustišek, Nives   +2 more
  +7 more sources

Hyper-dilute botulinum toxin as an effective treatment for refractory erythromelalgia [PDF]

JAAD Case Reports
Ariel Brown, BA, Duaa AbdelHameid, MD, Kaveh Nezafati, MD, Heather W. Goff, MD, MPH   +3 more
doaj   +2 more sources

Hereditary cold-induced palmar erythema with dysesthesia: A novel entity with response to onabotulinumtoxinA injections [PDF]

JAAD Case Reports
Injae Jung, BS, Shena Kravitz, MD, John Linabury, DO   +2 more
doaj   +2 more sources