Results 71 to 80 of about 3,693 (191)

Újdonságok, aktualitások a polycythaemia vera diagnosztikájában és kezelésében | Diagnosis and treatment of polycythaemia vera: state of the art [PDF]

, 2016
Absztrakt A polycythaemia vera a Philadelphia-negatív krónikus myeloid neoplasiák közé tartozó ritka neoplasia, amelyre az emelkedett vörösvérsejttömeg okozta hiperviszkozitás a jellemző.
Borbényi, Zita, Marton, Imelda, Simon, Zsófia   +2 more
core   +1 more source

Pain management in children with erythromelalgia: case report [PDF]

Revista Brasileira de Anestesiologia, 2018
Erythromelalgia is a neuropathic pain syndrome due to an autosomal dominant gene, characterized by erythema, increased skin temperature and burning pain in hands and feet, whose treatment is often unsatisfactory.
Estela Irene Bortoli, Rioko Kimiko Sakata   +1 more
doaj   +3 more sources

Genetic neurological channelopathies: molecular genetics and clinical phenotypes [PDF]

, 2015
Evidence accumulated over recent years has shown that genetic neurological channelopathies can cause many different neurological diseases. Presentations relating to the brain, spinal cord, peripheral nerve or muscle mean that channelopathies can impact ...
Hanna, MG, Kullmann, DM, Spillane, J
core   +1 more source

Expert Perspective: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, Volume 77, Issue 10, Page 1305-1316, October 2025.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Synergistic Inhibition of Nav1.7 and NCX1: A Novel Strategy for Treating Cancer‐Induced Bone Pain by Modulating Pain Sensitization and Neuronal Inflammation

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
Nav1.7‐mediated sodium influx promotes NCX1 reverse transport, increasing sensory neuron excitability and causing calcium overload, which activates the p38 MAPK/NF‐κB pathway and induces neuroinflammation. Dual inhibition reduces hyperexcitability, restores calcium homeostasis, suppresses neuroinflammation, and ultimately alleviates cancer‐induced bone
Yan Feng, Fang Yan, Dongtai Chen, Peizong Wang, Yan Yan, Xiangnan Chen, Qiang Li, Wei Xing, Weian Zeng, Yang Huang   +9 more
wiley   +1 more source

Thermosensory Roles of G Protein‐Coupled Receptors and Other Cellular Factors in Animals

BioEssays, Volume 47, Issue 3, March 2025.
Recent studies have revealed GPCR functions in temperature sensation. This article introduces dual thermosensing via GPCRs and TRP channels associated with the intracellular signaling components and cellular factors such as lipid interactions and pH changes, highlighting the complexity of the temperature sensing mechanism.
Kohei Ohnishi, Takaaki Sokabe
wiley   +1 more source

Erythromelalgia? A Clinical Study of People Who Experience Red, Hot, Painful Feet in the Community

International Journal of Vascular Medicine, 2013
We recruited a population of people who clinically suffer from the symptoms of erythromelalgia, red, hot, painful feet made worse by heat and improved by cooling, to better characterise this population and measure their quality of life (QOL). Ninety-two
D. Friberg, T. Chen, G. Tarr, A. van Rij
doaj   +1 more source

Benefit-risk profile of cytoreductive drugs along with antiplatelet and antithrombotic therapy after transient ischemic attack or ischemic stroke in myeloproliferative neoplasms [PDF]

, 2018
We analyzed 597 patients with myeloproliferative neoplasms (MPN) who presented transient ischemic attacks (TIA, n = 270) or ischemic stroke (IS, n = 327). Treatment included aspirin, oral anticoagulants, and cytoreductive drugs.
Arellano-Rodrigo, Eduardo, Barbui, Tiziano, Beggiato, Eloise, Bellini, Marta, Bertozzi, Irene, Betti, Silvia, Bonifacio, Massimiliano, Cacciola, Emma, Cacciola, Rossella, Carli, Giuseppe, Carobbio, Alessandra, Cattaneo, Daniele, Cazzola, Mario, Censori, Bruno, Cervantes, Francisco, Cortelezzi, Agostino, De Stefano, Valerio, Di Lazzaro, Vincenzo, Elli, Elena Maria, Ellis, Martin H., Finazzi, Guido, Finazzi, Maria Chiara, Gaidano, Gianluca, Gomez, Montse, Griesshammer, Martin, Guglielmelli, Paola, Hernandez-Boluda, Juan-Carlos, Iurlo, Alessandra, Loscocco, Giuseppe Gaetano, Lunghi, Francesca, Miroslava, Palova, Musolino, Caterina, Palandri, Francesca, Randi, Maria Luigia, Rapezzi, Davide, Rossi, Elena, Rumi, Elisa, Sadjadian, Parvis, Scaffidi, Luigi, Tieghi, Alessia, Vannucchi, Alessandro M., Vianelli, Nicola   +41 more
core   +5 more sources

Cutaneous reactions to vaccination

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 2, Page 195-209, February 2025.
Summary Vaccination is a fundamental principle of preventive health care. Administration of the vaccine, which contains the antigen(s) of a pathogen, activates the immune system and provides protection against infection. The immunogenicity and allergenicity of a vaccine may lead to various adverse reactions, depending on the responsiveness and ...
Jacqueline Kussini, Stefan Mühlenbein, Dario Didona, Wolfgang Pfützner   +3 more
wiley   +1 more source

Applying consensus criteria to the evaluation of patients with suspected chronic lymphocytic leukemia/small lymphocytic lymphoma [PDF]

, 2014
We describe a series of 5 patients in whom the application of consensus criteria for the diagnosis of chronic lymphocytic leukemia (CLL) led to a revised diagnosis.
Malkit, Riyat, Mulwa-Babu, E., Parech, D.   +2 more
core   +2 more sources