Results 241 to 250 of about 94,345 (348)

Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis

Brain and Behavior, Volume 16, Issue 1, January 2026.
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo, Yujie Yang, Xiaojian Cao, Chunchu Deng, Hong Chen   +4 more
wiley   +1 more source

Residual Genetic Material in Mature Red Blood Cells. [PDF]

Int J Mol Sci
Dryllis G, Fortis SP, Kouroupaki A, Tsamesidis I, Birtsas V, Tsantes AG, Valsami S, Konstantopoulos K, Papageorgiou EG, Pessach I, Kriebardis AG.   +10 more
europepmc   +1 more source

Theranostic Nanoparticles in Prostate Cancer: Disrupting Hypoxia‐Induced Glycolysis by Targeting Hypoxia‐Inducible Factor‐1 Alpha and Downstream Metabolites

Cancer Medicine, Volume 15, Issue 1, January 2026.
The debate in the field of cancer immunotherapy is being changed as nanotechnology breaks the obstacle of cancer immune evasion, target delivery, and systemic toxicity. Esthetically advanced methods that are discussed in this review are nanovaccine, nanoparticle‐enabled checkpoint barrier, cytokine delivery, and T‐cell modulation techniques that ...
Daniel Ejim Uti, Wilson Achu Omang, Esther Ugo Alum, Inalegwu Bawa, Okechukwu Paul‐Chima Ugwu, Ayodeji Oluwafemi Idowu, Item Justin Atangwho, Godwin Eneji Egbung   +7 more
wiley   +1 more source

Monge's disease at 100 years: Revisiting the origins and endocrine mechanisms of chronic mountain sickness. [PDF]

Sci Prog
Gonzales GF.
europepmc   +1 more source

Peri‐operative haemoglobin trajectories in patients without pre‐operative anaemia undergoing valvular heart surgery

Anaesthesia, Volume 81, Issue 2, Page 291-293, February 2026.
Hee Won Choi, Hyun‐Soo Zhang, Jae‐Kwang Shim, Young Lan Kwak   +3 more
wiley   +1 more source

Tofacitinib Use in a Patient With Rheumatoid Arthritis and Polycythemia Vera: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and joint destruction, whereas polycythemia vera (PV) is a myeloproliferative neoplasm driven by the Janus kinase (JAK)2 V617F mutation, resulting in erythrocytosis and increased thromboembolic risk.
Milan Bogojevic, Rifat Medjedovic, Milica Markovic, Nikola Bakic, Dragana Pravilovic Lutovac   +4 more
wiley   +1 more source

Novel agents and evolving strategies for anemia management in lower-risk myelodysplastic syndromes. [PDF]

Blood Res
Hong J.
europepmc   +1 more source

Outline of Iron Metabolism, with Emphasis on Erythroid Cells. [PDF]

Mediterr J Hematol Infect Dis
Testa U, Pelosi E, Castelli G.
europepmc   +1 more source

First‐In‐Human Study to Assess the Pharmacokinetics and Safety of DS‐6016a After Single Subcutaneous Injection in Healthy Japanese Adults

Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Fibrodysplasia ossificans progressiva is a rare, progressive autosomal dominant genetic disease caused by an activin receptor‐like kinase 2 (ALK2) mutation with a need for effective prophylactic therapies. This single‐center, randomized, double‐blind, placebo‐controlled study evaluated the pharmacokinetics and safety of DS‐6016a, a novel ...
Kei Okita, Hidetoshi Furuie, Akifumi Kurata, Yasuko Owada, Satoshi Yoshiba, Kei Furihata, Takaaki Oka, Yushi Kashihara, Hitoshi Ishizuka, Kazutaka Yoshihara   +9 more
wiley   +1 more source

Inhibition of XPO1 by selinexor enhances terminal erythroid maturation through modulation of HSP70 trafficking in severe β0-thalassemia/HbE. [PDF]

PLoS One
Khamphikham P, Tantiworawit A, Anuchapreeda S.   +2 more
europepmc   +1 more source