Results 251 to 260 of about 121,038 (379)

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, Volume 158, Issue 2, Page 357-367, 15 January 2026.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

Residual Genetic Material in Mature Red Blood Cells. [PDF]

Int J Mol Sci
Dryllis G, Fortis SP, Kouroupaki A, Tsamesidis I, Birtsas V, Tsantes AG, Valsami S, Konstantopoulos K, Papageorgiou EG, Pessach I, Kriebardis AG.   +10 more
europepmc   +1 more source

Phagocytosis of Lymphocytes and Erythrocytes by B‐Cell Lymphoma in a Patient With a Clinical Suspicion of Pure Red Cell Aplasia

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Herein, we report a diagnostically challenging case of a B‐cell lymphoma initially masquerading as pure red cell aplasia (PRCA). The key to diagnosis was the unique finding of phagocytic activity (engulfing erythrocytes and lymphocytes) by atypical mature lymphocytes in both peripheral blood and bone marrow, accompanied by clinical signs of ...
Tuo Cao, Yuting Li, Xiangming Peng
wiley   +1 more source

Monge's disease at 100 years: Revisiting the origins and endocrine mechanisms of chronic mountain sickness. [PDF]

Sci Prog
Gonzales GF.
europepmc   +1 more source

A slow burn: Revisiting cross‐adaptation through long‐term heat acclimation

Experimental Physiology, EarlyView.
Elliott J. Jenkins, Michael Stembridge
wiley   +1 more source

Drug Repositioning of Pegbing® for Essential Thrombocythemia: Insights from PK/PD Modeling and Extrapolation

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 219-227, January 2026.
Pegbing® (peginterferon alfa‐2b), a pegylated interferon‐alpha, is approved for the treatment of chronic hepatitis B (CHB) and C. One of its adverse effects is platelet (PLT) suppression. It is currently being repurposed for the treatment of essential thrombocythemia (ET), a rare myeloproliferative disorder characterized by abnormally elevated PLT ...
Weizhe Jian, Yalin Yin, Rong Chen, Junsheng Xue, Jianbo Gu, Zhengfang Du, Ruoyi He, Tianyan Zhou   +7 more
wiley   +1 more source

Novel agents and evolving strategies for anemia management in lower-risk myelodysplastic syndromes. [PDF]

Blood Res
Hong J.
europepmc   +1 more source

High‐Dose Parenteral Iron Corrects Iron Deficiency Anemia While Disrupting Gut Microbiota and Metabolic Homeostasis in Neonatal Piglets

Food Frontiers, Volume 7, Issue 1, January 2026.
Our results indicate that although high‐dose parenteral iron effectively corrects iron deficiency anemia (IDA), it causes liver dysfunction, immune suppression, systemic iron overload, and altered gut microbiota. ABSTRACT Iron deficiency anemia (IDA) is a common nutritional disorder in mammals, particularly affecting neonates and neonatal piglets ...
Qian Zhang, Yubin Hao, Xin Tian, Xuejiao Li, Jie Feng   +4 more
wiley   +1 more source

Outline of Iron Metabolism, with Emphasis on Erythroid Cells. [PDF]

Mediterr J Hematol Infect Dis
Testa U, Pelosi E, Castelli G.
europepmc   +1 more source

A Global Metabolomic and Lipidomic Landscape of Human Plasma Across the Lifespan

Aging Cell, Volume 25, Issue 1, January 2026.
Liu et al. provide a comprehensive analysis of dynamic plasma metabolomic and lipidomic changes in humans across the lifespan, identifying age‐specific metabolic trajectories and developing a metabolite‐based aging clock, offering insights into metabolic reprogramming and potential biomarkers for aging‐related health interventions.
Xinru Liu, Tingting Liang, Rui Zhao, Mingming Zhu, Beibei Huang, Xiaobi Huang, Fang Ni   +6 more
wiley   +1 more source