The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang +8 more
wiley +1 more source
Stem Cell Steal After Intravenous Iron: A Case of Transient Thrombocytopenia in Severe Iron Deficiency Anaemia. [PDF]
Dirican CD +4 more
europepmc +1 more source
ABSTRACT Administration of memantine, an antagonist of the N‐methyl‐ d‐aspartate receptor, prevents Ca2+ overload and dehydration of red blood cells (RBCs) in patients with sickle cell disease (SCD). The objectives of the 1‐year dose‐escalation Phase IIa/IIb Memantine trial (MeMAGEN – NCT 03247218) with 17 SCD patients who were under stable ...
Ariel Koren +7 more
wiley +1 more source
The oncogene protein kinase PIM1 regulates mammalian erythroblast enucleation. [PDF]
Zhang H +8 more
europepmc +1 more source
Abstract Hereditary anemias encompass a genetically heterogeneous spectrum of disorders, often involving multi‐locus inheritance, which can complicate clinical management and worsen disease severity. This study investigates the impact of the co‐inheritance of SEC23B loss‐of‐function pathogenic variants, which lead to congenital dyserythropoietic anemia
Antonella Nostroso +19 more
wiley +1 more source
Comparative circRNA Profiling in Human Erythroblasts Derived from Fetal Liver and Bone Marrow Hematopoietic Stem Cells Using Public RNA-Seq Data. [PDF]
Habara A.
europepmc +1 more source
Elevated Endogenous Alveolar Carbon Monoxide Concentration in Patients with Transfusion-Dependent Thalassemia and Its Relation with Ineffective Erythropoiesis. [PDF]
Xie Y +17 more
europepmc +1 more source
Author Correction: JK-1, a useful erythroleukemic cell line model to study a controlled erythroid differentiation from progenitors to terminal erythropoiesis [PDF]
Sylvain Métral +3 more
openalex +1 more source
Abstract Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosomal proteins, including RPS19, a component of the 40S ribosomal subunit.
Juraj Kokavec +13 more
wiley +1 more source
Rapid increase in erythropoiesis-stimulating agent resistance is a risk factor for poor renal prognosis in patients with chronic kidney disease pre-dialysis: A BRIGHTEN study sub-analysis. [PDF]
Kawamoto S +5 more
europepmc +1 more source

