Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
The oncogene protein kinase PIM1 regulates mammalian erythroblast enucleation. [PDF]
Zhang H +8 more
europepmc +1 more source
Efficacy of Momelotinib in Myelofibrosis Patients: Results From a Multicenter Study
ABSTRACT Momelotinib, a novel JAK1/2 inhibitor with inhibitory activities on activin A receptor type I, has shown breakthrough clinical efficacy in patients with myelofibrosis (MF) and anemia, a disease‐related manifestation of challenging management. In this retrospective real‐life multicenter Italian study, we investigated the safety and efficacy of ...
Maria Carmen Martorelli +34 more
wiley +1 more source
Comparative circRNA Profiling in Human Erythroblasts Derived from Fetal Liver and Bone Marrow Hematopoietic Stem Cells Using Public RNA-Seq Data. [PDF]
Habara A.
europepmc +1 more source
Modulistat, a PHD inhibitor, ameliorated erythropoiesis in adenine-induced nephropathy mice
Daisuke Nakano, Lei Li, Akira Nishiyama
openalex +2 more sources
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro +22 more
wiley +1 more source
Rapid increase in erythropoiesis-stimulating agent resistance is a risk factor for poor renal prognosis in patients with chronic kidney disease pre-dialysis: A BRIGHTEN study sub-analysis. [PDF]
Kawamoto S +5 more
europepmc +1 more source
HIF‐prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism
V. Haase
semanticscholar +1 more source
Abstract The therapeutic landscape for renal cell carcinoma (RCC) and urinary tract cancer (UTC) has transformed dramatically, creating complexity in treatment selection and sequencing. The 2025 Advanced Urologic Cancer Consensus Conference was convened to establish evidence‐based expert consensus recommendations for optimal management.
Rana R. McKay +53 more
wiley +1 more source

