Results 131 to 140 of about 16,252 (181)
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Pediatrics In Review, 1991
Cloning and expression of the human gene encoding erythropoietin has resulted in the availability of recombinant erythropoietin for clinical and laboratory investigation. Results of such investigations are clarifying the mechanisms that regulate production of erythropoietin in health and disease.
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Cloning and expression of the human gene encoding erythropoietin has resulted in the availability of recombinant erythropoietin for clinical and laboratory investigation. Results of such investigations are clarifying the mechanisms that regulate production of erythropoietin in health and disease.
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Novel applications of recombinant erythropoietin
Current Opinion in Pharmacology, 2006Recombinant erythropoietin (EPO) was introduced into clinical practice after the identification of EPO as the major haemopoietic growth factor determining survival and maturation of erythroid precursors. Advances in our understanding of the novel sites of action of EPO in the vasculature, brain, heart and kidney have opened new avenues of therapeutic ...
Edward J, Sharples +2 more
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Intraperitoneal Administration of Recombinant Human Erythropoietin
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 1992Objective To determine the efficacy and safety of intraperitoneal administration of recombinant human erythropoietin (rHuEPO) in continuous ambulatory peritoneal dialysis (CAPD) patients compared to subcutaneous rHuEPO.
Frenken, L. A. +5 more
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The production of recombinant human erythropoietin
1995Erythropoietin (EPO) is the glycoprotein hormone that promotes differentiation of erythroid progenitor cells in bone marrow. The normal kidney produces EPO to maintain erythrocyte for oxygen supply. This hormone activity was found in the serum of anemic animals in the 1890s.
N, Inoue +3 more
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Recombinant Erythropoietin and Analogues
Therapeutic Drug Monitoring, 2004Erythropoietin (EPO) increases the number of circulating erythrocytes and thus muscle oxygenation. The availability of the recombinant protein (rEPO) has increased the risk of its illegal use in sports, its detection being a difficult challenge.
J A, Pascual +5 more
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Recombinant Erythropoietin and Medicare Payment
JAMA: The Journal of the American Medical Association, 1991To the Editor. —The article by Sisk et al 1 provided an informative account of the Medicare experience to date in coverage of erythropoietin. The conclusions, however, seemed unduly critical of the role of the Health Care Financing Administration (HCFA) in (1) the initial pricing of this drug; (2) the dosage levels given; and (3) the monitoring of its
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