Results 101 to 110 of about 60,176 (280)

Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells [PDF]

open access: yes, 2014
Endothelial colony-forming cells (ECFCs) are obtained from the culture of human peripheral blood mononuclear cell (hPBMNC) fractions and are characterised by high proliferative and pro-vasculogenic potential, which makes them of great interest for cell ...
A Kawabata   +41 more
core   +6 more sources

Prognostic impact of iron deficiency in new‐onset chronic heart failure: Danish Heart Failure Registry insights

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1346-1357, April 2025.
Abstract Aims Iron deficiency (ID) is prevalent in chronic heart failure (HF) but lacks a consensus definition. This study evaluates the prevalence and the prognostic impact of ID using different criteria on all‐cause and cardiovascular mortality, as well as first hospitalization for HF in patients with new‐onset chronic HF.
Abdullahi Ahmed Mohamed   +12 more
wiley   +1 more source

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

open access: yesFood Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo   +8 more
wiley   +1 more source

The Role of Erythropoietin as an Inhibitor of Tissue Ischemia

open access: yesInternational Journal of Biological Sciences, 2008
Erythropoietin is a hypoxia-induced cytokine that stimulates erythropoiesis through the promotion of erythroid precursor cell proliferation and differentiation.
Marios G. Lykissas, Alexandros E. Beris
doaj  

Gamma-Aminobutyric Acid Increases Erythropoietin by Activation of Citrate Cycle and Stimulation of Hypoxia-Inducible Factors Expression in Rats

open access: yesBiomolecules, 2020
Erythropoietin (EPO) is the primary regulator of erythropoiesis in the mammalian fetus and adult. Deficiency of EPO induces anemia. In this study, we investigated the effect of gamma-aminobutyric acid (GABA) on serum EPO levels and erythropoiesis in rats.
Keun-Tae Park   +3 more
doaj   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

Erythropoietin critically regulates the terminal maturation of murine and human primitive erythroblasts

open access: yesHaematologica, 2013
Primitive erythroid cells, the first red blood cells produced in the mammalian embryo, are necessary for embryonic survival. Erythropoietin and its receptor EpoR, are absolutely required for survival of late-stage definitive erythroid progenitors in the ...
Jeffrey Malik   +4 more
doaj   +1 more source

Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells [PDF]

open access: yes, 2019
There are conflicting reports on the adverse effects of erythropoietin (EPO) for the management of cancer-associated anemia. The recognition that erythropoietin receptors (EPORs) are expressed outside the erythroid lineage and concerns that ...
Benchimol, Samuel   +4 more
core   +2 more sources

Inflammation and Erythropoietin Resistance in Chronic Kidney Disease: A Cross‐Sectional Study of C‐Reactive Protein and Anemia in Hemodialysis Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study examined the role of inflammation in anemia among patients with chronic kidney disease on maintenance hemodialysis. Elevated C‐reactive protein (CRP) levels were associated with reduced iron availability, lower hematocrit, and increased erythropoietin requirements.
Collince Odiwuor Ogolla   +3 more
wiley   +1 more source

Bone marrow mesenchymal stem cells transplantation promotes the release of endogenous erythropoietin after ischemic stroke

open access: yesNeural Regeneration Research, 2015
This study investigated whether bone marrow mesenchymal stem cell (BMSC) transplantation protected ischemic cerebral injury by stimulating endogenous erythropoietin.
Wen Lv   +4 more
doaj   +1 more source

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