Results 111 to 120 of about 15,562 (220)

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu   +4 more
wiley   +1 more source

Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe   +5 more
wiley   +1 more source

Changes in the cervicovaginal microbiota composition of HPV16‐infected patients after clinical treatment

open access: yesCancer Medicine, Volume 11, Issue 24, Page 5037-5049, December 2022., 2022
This study interpreted the differential profiles of cervicovaginal microbiota and CSTs between HC women and HPV16‐infected women with CIN I, CIN II/III or SCC. The relationship between HPV16 clearance and cervicovaginal microbiota composition in each disease stage before and after clinical treatments was also established.
Chao Li   +3 more
wiley   +1 more source

Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space

open access: yesAngewandte Chemie, EarlyView.
We optimized mixed peptide‐peptoid sequences for molecular similarity to the macrocyclic lipopeptide antibiotic polymyxin B2 (PMB2) using a genetic algorithm. Synthesis and testing of top‐scoring compounds allowed us to identify new macrocycles with similar antimicrobial activity and reduced toxicity compared to PMB2.
Etienne Bonvin   +7 more
wiley   +2 more sources

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