Results 291 to 300 of about 1,005,431 (399)

Intact Proteoform Analysis by Capillary Electrophoresis–Mass Spectrometry. Are We There Yet?

open access: yesAngewandte Chemie, EarlyView.
Mass spectrometry (MS) and top–down proteomics (TDP) have emerged as powerful tools to decipher proteoform‐level information, advancing biological insight and translational research. This study unites leaders in capillary electrophoresis (CE) and MS from multiple institutions across the globe to showcase the reproducibility, unique information, and ...
Noah Gould   +33 more
wiley   +2 more sources

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

open access: yesAngewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan   +3 more
wiley   +2 more sources

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

open access: yesAngewandte Chemie, EarlyView.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler   +4 more
wiley   +2 more sources

Non-O157 Shiga toxin-producing Escherichia coli infections in the United States, 1983-2002.

open access: yesJournal of Infectious Diseases, 2005
J. Brooks   +6 more
semanticscholar   +1 more source

Heteromultivalent Nanogels as Highly Potent Inhibitors of Pseudomonas Aeruginosa

open access: yesAngewandte Chemie International Edition, EarlyView.
A heteromultivalent polyglycerol nanogel system integrates fucose/galactose and short‐chain antibacterial peptides to achieve strong bactericidal and anti‐biofilm effects at low concentration by efficient multivalent binding with bacterial lectins.
Yuhang Jiang   +8 more
wiley   +1 more source

Group B Streptococcus and Escherichia coli Infections in the Intensive Care Nursery in the Era of Intrapartum Antibiotic Prophylaxis

open access: yesThe Pediatric Infectious Disease Journal, 2012
Melissa S. Bauserman   +7 more
semanticscholar   +1 more source

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