Isolation, characterization and genomic analysis of a novel lytic bacteriophage EcoPhCCP1, capable of infecting multiple strains of multidrug-resistant <i>Escherichia coli</i> recovered from urinary tract infections. [PDF]
Parra B +6 more
europepmc +1 more source
Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source
Crystal structure of PM1Pgh, a poly-γ-glutamate hydrolase from Bacillus phage PM1. [PDF]
Abe K, Fukui K, Ogura Y.
europepmc +1 more source
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui +8 more
wiley +1 more source
Unveiling Novel Lytic Bacteriophages as Natural Biocontrol Agents Against Multidrug-Resistant Escherichia coli: Isolation, Characterization, and In vitro Application. [PDF]
Tasdurmazli S +5 more
europepmc +1 more source
CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen +11 more
wiley +1 more source
Establishment of a stable monoculture system for <i>Entodinium furca monolobum</i> and isolation of <i>Escherichia</i> spp. as growth-promoting bacteria. [PDF]
Wang Y +11 more
europepmc +1 more source
Digital seed amplification assay for TDP‐43 aggregate quantification in CSF
Abstract INTRODUCTION Dementia is commonly caused by underlying pathologies driven by misfolded protein aggregates. Although dementia subtypes have distinct mechanisms, overlapping symptoms make diagnosis without biomarkers difficult. Misdiagnosis has previously hindered drug development by enrolling patients non‐specifically in trials.
Ella Borberg +7 more
wiley +1 more source
Vaccine Candidates Designed to Prevent Enterotoxigenic Escherichia coli Diarrhoea: A Scoping Review of Clinical Trials Evaluating Vaccine Candidates in Development. [PDF]
Nafade V +4 more
europepmc +1 more source
Systemic immune dysregulation in patients experiencing urogynaecological mesh failure
Abstract Objectives This study aimed to investigate the systemic immune landscape in patients experiencing urogynaecological mesh failure. The use of urogynaecological mesh was paused in the UK following an independent safety review that found ~1 in 15 women required removal due to complications. However, the mechanisms underpinning mesh failure remain
Shannon Jamieson +9 more
wiley +1 more source

