Isolation and Functional Characterization of an Acidic Myotoxic Phospholipase A2 from Colombian Bothrops asper Venom [PDF]
Toxins, 2017 Myotoxic phospholipases A2 (PLA2) are responsible for many clinical manifestations in envenomation by Bothrops snakes. A new myotoxic acidic Asp49 PLA2 (BaCol PLA2) was isolated from Colombian Bothrops asper venom using reverse-phase high performance ...
Silvia Posada Arias +7 more
doaj +2 more sources
Inhibition of a Snake Venom Metalloproteinase by the Flavonoid Myricetin [PDF]
Molecules, 2018 Most of the snakebite envenomations in Central and South America are caused by species belonging to Bothrops genus. Their venom is composed mainly by zinc-dependent metalloproteinases, responsible of the hemorrhage characteristic of these envenomations ...
Lina María Preciado +4 more
doaj +2 more sources
Snake venomics of Bothrops punctatus, a semiarboreal pitviper species from Antioquia, Colombia [PDF]
PeerJ, 2014 Bothrops punctatus is an endangered, semi-arboreal pitviper species distributed in Panamá, Colombia, and Ecuador, whose venom is poorly characterized.
Maritza Fernández Culma +3 more
doaj +3 more sources
O combate ao escorpionismo [PDF]
Memorias do Instituto Oswaldo Cruz, 1946 O outor estuda os processos de combate aos acidentes pelas picadas dos escorpiões, visando: a) Profilaxia e b) Terapêutica. Refere-se à luta nos campos e nas cidades e aqui, dentro e fora dos domicílios.
Octavio de Magalhães
doaj +3 more sources
MipLAAO, a new L-amino acid oxidase from the redtail coral snake Micrurus mipartitus [PDF]
PeerJ, 2018 L-amino acid oxidases (LAAOs) are ubiquitous enzymes in nature. Bioactivities described for these enzymes include apoptosis induction, edema formation, induction or inhibition of platelet aggregation, as well as antiviral, antiparasite, and antibacterial
Paola Rey-Suárez +5 more
doaj +3 more sources
Sulfur Compounds as Inhibitors of Enzymatic Activity of a Snake Venom Phospholipase A2: Benzyl 4-nitrobenzenecarbodithioate as a Case of Study [PDF]
Molecules, 2020 Snakebite is a neglected disease with a high impact in tropical and subtropical countries. Therapy based on antivenom has limited efficacy in local tissue damage caused by venoms. Phospholipases A2 (PLA2) are enzymes that abundantly occur in snake venoms
Isabel Henao Castañeda +3 more
doaj +2 more sources
Padrões espaço-temporais do escorpionismo em Alagoas, nordeste do Brasil:
Diversitas Journal, 2023 A alta incidência de escorpionismo na saúde pública no Brasil e demais países em desenvolvimento, motivou sua inclusão na lista de Doenças Tropicais Negligenciadas da Organização Mundial de Saúde. Destarte, o objetivo do estudo foi investigar a dinâmica
João Lucas Cavalcante Santos +6 more
doaj +3 more sources
Interactions between Triterpenes and a P-I Type Snake Venom Metalloproteinase: Molecular Simulations and Experiments [PDF]
Toxins, 2018 Small molecule inhibitors of snake venom metalloproteinases (SVMPs) could provide a means to rapidly halt the progression of local tissue damage following viperid snake envenomations.
Lina María Preciado +3 more
doaj +2 more sources
Synthetic Inhibitors of Snake Venom Enzymes: Thioesters Derived from 2-Sulfenyl Ethylacetate [PDF]
Pharmaceuticals, 2019 Snakebite envenomings are a global public health issue. The therapy based on the administration of animal-derived antivenoms has limited efficacy against the venom-induced local tissue damage, which often leads to permanent disability.
Isabel C. Henao Castañeda +2 more
doaj +2 more sources
Características epidemiológicas das vítimas de Escorpionismo na Bahia [PDF]
Brazilian Journal of Health Review, 2023 Objetivo: Investigar o perfil epidemiológico dos casos de escorpionismo na Bahia. Métodos: Esta pesquisa consistiu em uma revisão integrativa da literatura utilizando as bases de dados MEDLINE e LILACS, através do Portal Biblioteca Virtual em Saúde (BVS)
Andrade, Gustavo Bittencourt Coutinho +9 more
core +3 more sources