Results 1 to 10 of about 361,011 (158)

Protocol for generating human cerebral organoids from two-dimensional cultures of pluripotent stem cells bypassing embryoid body aggregation [PDF]

STAR Protocols
Summary: Human cerebral organoids (hCOs) provide an excellent model for the study of human brain development and disease. Here, we present a protocol to obtain hCOs directly from two-dimensional (2D) pluripotent stem cell (PSC) cultures, avoiding cell ...
Rosa González-Sastre, Raquel Coronel, Patricia Mateos-Martínez, Laura Maeso, Elena Llorente-Beneyto, Alfonso Luque, Berta Anta, Victoria López-Alonso, Isabel Liste   +8 more
doaj   +2 more sources

Biological and molecular characterisation of in vitro selected miltefosine-resistant Leishmania amazonensis lines [PDF]

International Journal for Parasitology: Drugs and Drug Resistance
Miltefosine (MTF) is currently the only available oral treatment for leishmaniasis. However, increasing reports of therapeutic failure have raised concerns about emerging resistance.
Laura Fernanda Neira, Héllida Marina Costa-Silva, Juliana Martins Ribeiro, Silvane Maria Fonseca Murta, Patricia Escobar   +4 more
doaj   +2 more sources

Age as a Predictor of Overall Survival in Colorectal Cancer [PDF]

Diagnostics
Background: The diagnosis of colorectal cancer (CRC) at early ages has become a challenging trend for oncology due to high rates of mortality worldwide. The correlation of clinical features with young-age prognosis in CRC remains unclear.
Berenice Carbajal-López, Jossimar Coronel-Hernández, Marytere Herrera, Erika Ruiz-Garcia, Sayako M. Miyagui-Adame, Consuelo Diaz-Romero, Eduardo Osiris Madrigal-Santillán, Priscila Morales Esponda-Mendoza, Carlos Pérez-Plasencia, Germán Calderillo-Ruiz   +9 more
doaj   +2 more sources

Diagnostic accuracy of various anthropometric indexes for assessing insulin resistance in the Peruvian population: An analytical cross-sectional study [PDF]

Journal of Public Health Research
Background: Insulin resistance (IR) is a key driver of type 2 diabetes mellitus and cardiovascular diseases. Traditional methods for IR diagnosis are costly, highlighting the need for accessible alternatives like anthropometric indices.
Jamee Guerra Valencia, Noël C. Barengo, Diego Torres-Quispe, Lorena Saavedra-Garcia   +3 more
doaj   +2 more sources

Life Satisfaction and Family Communication as Protective Factors in Problematic Internet Use in University Students [PDF]

SAGE Open Nursing
Introduction Problematic Internet use (PIU) is considered a serious condition and a potential factor for various physical and psychological health problems, with higher prevalence rates in the young adult population, a situation aggravated by mandatory ...
Walter Capa-Luque, Luz Elizabeth Mayorga-Falcón, Evelyn Barboza Navarro, Armando Martínez Portillo, Yovana Pardavé-Livia, Aldo Bazán-Ramírez, Edmundo Hervias-Guerra, Catalina Bello-Vidal   +7 more
doaj   +2 more sources

Spatial variation of physicochemical parameters in a constructed wetland for wastewater treatment: An example of the use of the R programming language

Cuadernos de investigación UNED, 2021
Introduction: The implementation of wastewater treatment systems such as constructed wetlands has a growing interest in the last decade due to its low cost and high effectiveness in treating industrial and residential wastewater.
Junior Pastor Pérez-Molina, Carola Scholz, Roy Pérez-Salazar, Carolina Alfaro-Chinchilla, Ana Abarca Méndez, Leandro Araya Leitón, Jeslyn Carranza Chaves, Addy Echevarría Figueroa, Mariana Elizondo Blanco, Rachel Ardón Rivera, Sofía Flores Aguilar, Catalina Solís Calderón   +11 more
doaj   +1 more source

Bacterial multi-resistance to antibiotics in water from plant cavities (phytotelms) in a deep tropical forest from Costa Rica

Cuadernos de investigación UNED, 2023
Introduction: The spread of antimicrobial resistance in natural environments continues to be reported throughout the world; nevertheless, there is no study about phytotelms (water in the natural cavities of plants) in the deep understory of tropical ...
Stephanny Sánchez-Vargas, Paula Vargas-Jiménez, Luis Vega-Corrales, Junior Pastor Pérez-Molina   +3 more
doaj   +1 more source

Linking Anthropogenic Landscape Perturbation to Herbivory and Pathogen Leaf Damage in Tropical Tree Communities

Plants, 2023
Anthropogenic disturbance of tropical humid forests leads to habitat loss, biodiversity decline, landscape fragmentation, altered nutrient cycling and carbon sequestration, soil erosion, pest/pathogen outbreaks, among others.
José Luis Pablo-Rodríguez, Ángel E. Bravo-Monzón, Cristina Montiel-González, Julieta Benítez-Malvido, Sandra Álvarez-Betancourt, Oriana Ramírez-Sánchez, Ken Oyama, María Leticia Arena-Ortiz, Mariana Yólotl Alvarez-Añorve, Luis Daniel Avila-Cabadilla   +9 more
doaj   +1 more source

The Assembly of Tropical Dry Forest Tree Communities in Anthropogenic Landscapes: The Role of Chemical Defenses

Plants, 2022
The effect of anthropogenic disturbance on plant community traits and tradeoffs remains poorly explored in tropical forests. In this study, we aimed to identify tradeoffs between defense and other plant functions related to growth processes in order to ...
Ángel E. Bravo-Monzón, Cristina Montiel-González, Julieta Benítez-Malvido, María Leticia Arena-Ortíz, José Israel Flores-Puerto, Xavier Chiappa-Carrara, Luis Daniel Avila-Cabadilla, Mariana Yolotl Alvarez-Añorve   +7 more
doaj   +1 more source

Chlorophyll fluorescence and biomass partitioning within light and nitrogen deficiency: An example of the use of the R programming language for teaching

Cuadernos de investigación UNED, 2020
Introduction: Chlorophyll Fluorescence (Fv/Fm) detects damage in photosystem II (PSII) in plants exposed to stress (biotic and/or abiotic). Objective: In this context, Fv/Fm for the diagnosis of the effect of N deficiency and light in tomato plants ...
Junior Pastor Pérez-Molina, Raquel Castro Lara, Ian Portuguez Brenes, Valerie Araya Trejos, Andrey Quesada Traña   +4 more
doaj   +1 more source