Results 161 to 170 of about 25,570 (221)

Nitric Oxide Tunes Secreted Metabolite Bioactivity

Molecular Microbiology, Volume 126, Issue 2, Page 145-160, August 2026.
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan, Sarah L. Weisflog, Matthew Scurria, Jinyang Li, Korbinian Thalhammer, Osvaldo Gutierrez, Stuart J. Conway, Dianne K. Newman   +7 more
wiley   +1 more source

Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target. [PDF]

Neuron
Suresh A, Kourdougli N, Nomura T, Buth JE, Miranda-Rottmann S, Sánchez-León CA, Wu MW, Nelson SM, Wall LT, Tran AT, Araya R, Contractor A, Gandal MJ, Portera-Cailliau C.   +13 more
europepmc   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4823-4843, August 2026.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

Deciphering the immunomodulatory mechanisms of <i>Periplaneta americana L.</i> extract CII-3: insight from integrated metabolomics and network pharmacology. [PDF]

Front Cell Dev Biol
Wang Y, Wu Y, Liu X, Lu Z, Li T, Jin Y, Wang Y, Zhu J.   +7 more
europepmc   +1 more source

Rhizobacteria‐Induced Systemic Priming Against Fungal Pathogens Involves Hydroxycinnamic Acid Amides

Plant, Cell &Environment, Volume 49, Issue 8, Page 4907-4921, August 2026.
ABSTRACT The rhizosphere, a narrow region of soil surrounding roots, contains diverse microorganisms with a composition that is distinct from the surrounding soil. Some rhizosphere bacteria can trigger a heightened state of immunity in the whole plant, termed Induced Systemic Resistance (ISR).
Mackenzie Eli William Loranger, Wolfgang Moeder, Hyunsuh Lee, David K. Liscombe, Eric Déziel, Keiko Yoshioka   +5 more
wiley   +1 more source

A systematic review and meta-analysis on surgery for lumbar disc herniation: optimal timing of surgery, return to work and outcomes compared with conservative management. [PDF]

Brain Spine
Ambaliya S, De Bruyn F, Depreitere B.
europepmc   +1 more source

DNA Methylation Shapes Seed‐Borne Microbiome and Proteome Responses During Early Maize‐Beneficial Bacteria Interactions

Plant, Cell &Environment, Volume 49, Issue 8, Page 5477-5496, August 2026.
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli, Geovanna Vitória Olímpio, Felipe Astolpho de Almeida, Letícia Oliveira da Rocha, Diego Vinicius de Sena Martins, Sara Sangi, Fábio Lopes Olivares, Elyabe Monteiro de Matos, Juliana Siqueira, Lyderson Facio Viccini, Roberta Pena da Paschoa, Vanildo Silveira, Clícia Grativol   +12 more
wiley   +1 more source

Health Care Encounters and Expenditures Among Children With Diagnosed Tic Disorders and Co-Occurring Disorders, 2022. [PDF]

Psychiatr Serv
Wanga V, Danielson ML, Hong K, Hutchins HJ, Mathews CA, Mink JW, Gonzalez M, Grosse SD, Bitsko RH.   +8 more
europepmc   +1 more source

Chemical treatment rescues reduced growth of the autoimmune mutant chs3‐2D without compromising its immune responses

Plant Biology, Volume 28, Issue 5, Page 1686-1697, August 2026.
We generated a compound by chemical modification that can efficiently rescue growth without decreasing the immune response of the chs3‐2D autoimmune mutants, thus chemically uncoupling its growth–defence trade‐off. Abstract Plant development in many species including Arabidopsis relies on the accurate balance between growth and defence.
M. Keijzer, M. Liebers, J. Seufer, L. Voll, C. Meier, S. Hoth   +5 more
wiley   +1 more source