Results 61 to 70 of about 1,494,306 (302)

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud   +2 more
wiley   +1 more source

The 1688 Sannio–Matese Earthquake: A Dataset of Environmental Effects Based on the ESI-07 Scale

open access: yesData
The 1688 Sannio–Matese earthquake, with a macroseismically derived magnitude of Mw = 7 and an epicentral intensity of IMCS = XI, had a deep impact on Southern Italy, causing thousands of casualties, extensive damage and significant environmental effects (
Angelica Capozzoli   +4 more
doaj   +1 more source

Higher baseline global leukocyte DNA methylation is associated with MTX non-response in early RA patients

open access: yesArthritis Research & Therapy, 2019
Background Low-dose methotrexate (MTX) is the first-line therapy in early rheumatoid arthritis (eRA). Up to 40% of eRA patients do not benefit from MTX therapy.
Helen R. Gosselt   +5 more
doaj   +1 more source

Modulation of ion channels by natural products - identification of hERG channel inhibitors and GABAA receptor ligands from plant extracts [PDF]

open access: yes, 2014
Ion channels are expressed in virtually all cell types in the human body and are involved in various physiological processes. Hence, it is not surprising that ion channels play an important role in modern drug discovery.
Schramm, Anja
core   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt   +4 more
wiley   +1 more source

REGIONAL DEVELOPMENT THROUGH GROWTH AND URBAN DEVELOPMENT POLES IN ROMANIA [PDF]

open access: yesCES Working Papers, 2015
In 2008 the Ministry of Development, Public Works and Housing (now the Ministry of Regional Development and Public Administration) prepared the growth poles policy for Romania, establishing seven growth poles to be financed through the Regional ...
Stefana VARVARI, Marius CRISTEA
doaj  

Environmental sensitivity of the coastal islands of Ubatuba, SP, Brazil

open access: yesRevista Ambiente & Água, 2008
The Environmental Sensitivity Index Maps for Oil Spills (ESI Maps, or SAO in Portuguese) constitute an essential component and source of basic information for emergency planning, response decision support and damage evaluation in case of oil spills. This
Getulio Teixeira Batista   +1 more
doaj   +1 more source

Mass spectrometric analysis of pilus assembly, amyloid fibril formation, and membrane proteins in their native state [PDF]

open access: yes, 2012
Structural analysis of proteins and their complexes is crucial to understanding protein function. This thesis demonstrates the application of mass spectrometry (MS) to the study of pilus assembly on Gram-negative bacteria and amyloid formation in ...
Leney, Aneika Corrine
core  

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Competition and Excellence: Ranking of World-class Universities 2009 and Advance of Chinese Universities [PDF]

open access: yesJournal of Library and Information Studies, 2010
This paper evaluates the scientific competitiveness of world-class universities via their research output, with a focus on the position of Chinese universities in the world.
Jun-ping Qiu   +2 more
doaj  

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