Results 61 to 70 of about 25,570 (221)

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt, Adriana Arigò, Giorgio Famiglini, Pierangela Palma, Achille Cappiello   +4 more
wiley   +1 more source

Ecological Security Under the SPMOR Paradigm: Spatiotemporal Assessment of Fanjingshan Region (2002–2022)

Diversity
Ecological security is fundamental to achieving the United Nations Sustainable Development Goals (SDGs) and maintaining ecosystem stability in ecologically sensitive regions.
Runze Bao, Yuqiong Gao, Tianliang Yang, Fangxiang He, Yuxi Duan   +4 more
doaj   +1 more source

Selenium-Containing 1,4-Naphthoquinone Derivatives Trigger Reactive Oxygen Species and Apoptosis in Triple-Negative Breast Cancer Cells. [PDF]

Drug Dev Res
ABSTRACT Cancer ranks as a leading cause of death worldwide, demanding new affordable therapies. Nature offers a diverse array of bioactive scaffolds, including 1,4‐naphthoquinone, which serves as a precursor for numerous natural and synthetic compounds with potent antitumor properties.
Angulo-Elizari E, Raza A, Johnson H, Martínez-Sáez N, Encío I, Sharma AK, Sanmartín C, Plano D.   +7 more
europepmc   +2 more sources

The coastal record of tsunamis in the INQUA ESI-2007 scale

, 2014
Seismic Intensity scales are based on the effects of earthquakes on man, man-made structures and on natural environment. However, the effects on the environment have been usually minimized because they were considered as inaccurate features. The growth of Palaeoseismology as an independent discipline led to the development of the ESI-2007 Intensity ...
Bardají, Teresa, Silva, Pablo Gabriel, Zazo Cardeña, Caridad, Goy Goy, José Luis, Cabero, Ana, Lario Gómez, Javier   +5 more
openaire   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley   +1 more source

The 12 May 2008 Mw 7.9 Wenchuan, China, Earthquake: Macroseismic Intensity Assessment Using the EMS-98 and ESI 2007 Scales and Their Correlation with the Geological Structure

Bulletin of the Seismological Society of America, 2010
The Wenchuan earthquake of 12 May 2008 in Sichuan Province, China, can be classified as a large-scale event based on the tectonic structures that triggered the earthquake and the effects caused on the human, structural, and natural environment. This paper presents the geotectonic and seismotectonic regime of the earthquake-affected region on the basis
openaire   +2 more sources

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source