Results 51 to 60 of about 11,316 (216)
ALLELE-SPECIFIC TRANSCRIPTIONAL ACTIVITY OF THE VARIABLE NUMBER OF TANDEM REPEATS OF THE INDUCIBLE NITRIC OXIDE SYNTHASE GENE IS ASSOCIATED WITH IDIOPATHIC ACHALASIA [PDF]
Background: Polymorphisms of genes involved in the regulation of the immune response are risk factors for achalasia, but their contribution to disease pathogenesis is unknown.
Annese, Vito +12 more
core +1 more source
Achalasia is a rare disease that affects esophageal motility as result of myenteric denervation of the esophagus and in a large proportion of cases, stomach. Its causes remain still poorly elucidated and its diagnosis remains late, reporting a delay of at least 5 years from the onset of symptoms, often confused with conditions such as gastroesophageal ...
Cárcamo G., Leonardo +2 more
openaire +3 more sources
Current Status of Peroral Endoscopic Myotomy [PDF]
Peroral endoscopic myotomy (POEM) has been established as an optional treatment for achalasia. POEM is an endoluminal procedure that involves dissection of esophageal muscle fibers followed by submucosal tunneling.
Young Kwan Cho, Seong Hwan Kim
doaj +1 more source
The Mechanisms for the Association of Cancer and Esophageal Dysmotility Disorders
Background: Achalasia and other esophageal dysmotility disorders mimicking achalasia can be associated with cancer. This study aimed to review the main mechanisms for which cancer may develop in esophageal dysmotility disorder patients.
Francisco Tustumi +5 more
doaj +1 more source
Smooth muscle fascicular reorientation is required for esophageal morphogenesis and dependent on Cdo. [PDF]
Postnatal maturation of esophageal musculature involves proximal-to-distal replacement of smooth muscle with skeletal muscle by elusive mechanisms. We report that this process is impaired in mice lacking the cell surface receptor Cdo and identify the ...
Anthony I. Romer +40 more
core +2 more sources
High-resolution esophageal manometry in patients with achalasia
Introduction. At present, high-resolution esophageal manometry is the «gold standard» for the diagnosis of esophageal achalasia, based on the determination of the integrated relaxation pressure of the lower esophageal sphincter, the value of which in the
A. A. Smirnov +4 more
doaj +1 more source
A functional study of the esophagus in patients with non-cardiac chest pain and dysphagia [PDF]
Background/Aims: Nutcracker esophagus and non-specific motility disorders are the main causes of non-cardiac chest pain (NCCP), with gastroesophageal reflux in 60% of cases. Achalasia and diffuse esophageal spasm are the most frequent anomalies described
ALMASIO, Pier Luigi +7 more
core +1 more source
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar +5 more
wiley +1 more source
Achalasia cardia is the most common cause of motor dysphagia. Pneumatic dilation (PD) of lower esophageal sphincter remains the cornerstone of treatment. However, it is associated with esophageal perforation in some cases. We present a case of esophageal
Abhai Verma +3 more
doaj +1 more source
Background/Aims: Although an association between achalasia and esophageal cancer has been reported, whether achalasia confers a substantial increase in mortality is unknown.
Ga Hee Kim +18 more
doaj +1 more source

