Results 91 to 100 of about 115,341 (318)

L-Type Amino Acid Transporter-1 Overexpression and Melphalan Sensitivity in Barrett's Adenocarcinoma

open access: yesNeoplasia: An International Journal for Oncology Research, 2004
The L-type amino acid transporter-1 (LAT-1) has been associated with tumor growth. Using cDNA microarrays, overexpression of LAT-1 was found in 87.5% (7/8) of esophageal adenocarcinomas relative to 12 Barrett's samples (33% metaplasia and 66% dysplasia ...
Jules Lin   +9 more
doaj   +1 more source

EXPRESSION OF ENDOPLASMIC RETICULUM OXIDOREDUCTASES (EROS) AND THEIR ROLE IN THE GI TRACT [PDF]

open access: yes, 2012
It has been shown that some ER redox enzymes are differentially expressed in stomach and oesophagus tissue. The tissues of the gastrointestinal system, which are subject to external changes of environment during the process of digestion, represent a ...
WATSON, GRAEME
core  

The prevalence of viral agents in esophageal adenocarcinoma and Barrett’s esophagus: A systematic review [PDF]

open access: yes, 2017
Background & Aims: Human papillomavirus (HPV), which may reach the esophagus via orogenital transmission, has been postulated to be associated with esophageal adenocarcinoma.
Anderson, Lesley A.   +9 more
core   +1 more source

Influence of Hospital and Surgeon Volumes on Clinical Outcomes After Standard Surgery for Advanced Gastric Cancer: Supplementary Analysis of the Multicenter Randomized Phase III Trial JCOG1001

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We have evaluated interinstitutional variation to verify the generalization and standardization of gastric cancer surgery from a supplementary analysis of the randomized phase III trial JCOG1001. Although there was some degree of interinstitutional variation in short‐ and long‐term outcomes after standard gastric surgery, we found no correlation ...
Motohiro Hirao   +14 more
wiley   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe   +9 more
wiley   +1 more source

Ki-67 Antigen Overexpression Is Associated with the Metaplasia-Adenocarcinoma Sequence in Barrett's Esophagus

open access: yesGastroenterology Research and Practice, 2012
Introduction. The objective of this study was to evaluate Ki-67 antigen expression in patients with Barrett’s esophagus and esophageal adenocarcinoma and to assess its correlation with the metaplasia-esophageal adenocarcinoma progression. Methods.
Bernardo Silveira Volkweis   +5 more
doaj   +1 more source

Endoscopic screening for esophageal squamous cell carcinoma [PDF]

open access: yes, 2013
Esophageal cancer (EC) is the eighth common cancer and the sixth most common cause of death from cancer worldwide. Esophageal squamous cell carcinoma (ESCC) remains the most common type of EC in the developing world and an important health problem in ...
Amiriani, T.   +6 more
core  

Mepylome: A Point‐of‐Care Tumor Diagnostic Toolkit for Tumor DNA Methylation and Copy Number Analysis

open access: yesAdvanced Intelligent Systems, EarlyView.
DNA methylation and chromosomal copy number profiling have recently become essential for tumor diagnostics. The open‐source tool Mepylome enables this task in clinical routine. It combines several machine learning strategies and allows users to interactively examine respective data through an intuitive graphical interface. Running up to 65 times faster
Jon Brugger   +6 more
wiley   +1 more source

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