Results 111 to 120 of about 111,421 (336)

The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

International Journal of Cancer, EarlyView.
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley   +1 more source

Authentication of newly established human esophageal squamous cell carcinoma cell line (YM-1) using short tandem repeat (STR) profiling method [PDF]

, 2016
Cross-contamination during or early after establishment of a new cell line could result in the worldwide spread of a misidentified cell line. Therefore, newly established cell lines need to be authenticated by a reference standard method.
Ayyoob, K., Jahanbakhsh, A., Masoud, K., Vahideh, K.   +3 more
core  

Impact of Radiotherapy, Chemotherapy and Surgery in Multimodal Treatment of Locally Advanced Esophageal Cancer [PDF]

, 2011
Objectives: It was the aim of this study to assess our institutional experience with definitive chemoradiation (CRT) versus induction chemotherapy followed by CRT with or without surgery (C-CRT/S) in esophageal cancer.
Adams R, Annina Lemminger, Bedenne L, Berger B, Bernhard Berger, Claus Belka, Cooper JS, Delcambre C, Denham JW, Herskovic A, Katharina Stahlberg, Malthaner RA, Martin Bleif, Michael Bamberg, Minsky BD, Mizumoto M, Rades D, Sarraf M, Seung SK, Shi XH, Stahl M, Tepper J, Wolf M, Zhang Z   +23 more
core   +1 more source

Integrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome

International Journal of Cancer, EarlyView.
What's New? Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.
Minta Kärkkäinen, Tero Sievänen, Tia‐Marje Korhonen, Joonas Tuomikoski, Kirsi Pylvänäinen, Sami Äyrämö, Toni T. Seppälä, Jukka‐Pekka Mecklin, Eija K. Laakkonen, Tiina Jokela   +9 more
wiley   +1 more source

Esophageal Metastasis to the Iris Effectively Palliated Using Stereotactic Body Radiation Therapy and Adjuvant Intravitreal Chemotherapy: Case Report and Literature Review

Case Reports in Oncology, 2012
We report a case of isolated iris metastasis from esophageal adenocarcinoma that was successfully managed with local application of stereotactic body radiation therapy (SBRT) and adjunctive intravitreal therapy.
Sughosh Dhakal, Gareth M.C. Lema, David A. DiLoreto Jr, Alan W. Katz   +3 more
doaj   +1 more source

Body height and the excess cancer risk in men

International Journal of Cancer, EarlyView.
What's New? In cancers that affect both sexes, men usually have a higher risk than women. While this is often attributed to behavioral factors, such as exposure to environmental carcinogens, there may be an intrinsic biological mechanism involved. Tall stature has been associated with increased cancer risk.
Cecilia Radkiewicz, Gustaf Edgren, Arvid Sjölander, Emelie Benyi, Mats Lambe, Paul W. Dickman, Lars Sävendahl   +6 more
wiley   +1 more source

Barrett's Esophageal Adenocarcinoma with Neuroendocrine Cell Carcinoma Treated by Endoscopic Submucosal Dissection: A Case Report and Literature Review. [PDF]

DEN Open
ABSTRACT Barrett's esophageal adenocarcinoma (BEA) with neuroendocrine cell carcinoma (NEC) is a rare disease with a poor prognosis. We report a case of BEA with NEC treated by endoscopic submucosal dissection (ESD) with en bloc resection and long‐term survival was achieved without additional treatment.
Kubota Y, Ishido K, Doi K, Kitahara G, Wada T, Watanabe A, Ikehara H, Kusano C.   +7 more
europepmc   +2 more sources

RETRACTED ARTICLE: STMN-1 is a potential marker of lymph node metastasis in distal esophageal adenocarcinomas and silencing its expression can reverse malignant phenotype of tumor cells [PDF]

, 2014
BACKGROUND: Distal esophageal adenocarcinoma is a highly aggressive neoplasm. Despite advances in diagnosis and therapy, the prognosis is still poor. Stathmin (STMN-1) is a ubiquitously expressed microtubule destabilizing phosphoprotein.
Che Yu, Chen-Sheng Li, Hong-Jun Liu, Javed Akhtar, Yu-Long Shi, Zhou Wang   +5 more
core   +1 more source

P66shc and its downstream Eps8 and Rac1 proteins are upregulated in esophageal cancers

Cell Communication and Signaling, 2010
Members of Shc (src homology and collagen homology) family, p46shc, p52shc, p66shc have known to be related to cell proliferation and carcinogenesis.
Wani Nisar A, Naqash Sameer, Hamza Rouf, Baba Rafia A, Bhat Hina F, Kirmani Deeba, Bashir Muneesa, Andrabi Khurshid I, Zargar Mohammad A, Khanday Firdous A   +9 more
doaj   +1 more source

Adjuvant nivolumab after chemoradiotherapy and resection for patients with esophageal cancer: A real‐world matched comparison of overall survival

International Journal of Cancer, EarlyView.
What's New? Patients with esophageal or gastroesophageal junction (GEJ) cancer with residual disease after treatment with neoadjuvant chemoradiotherapy (nCRT) and resection frequently experience poor survival. Improvements in outcome, however, may be possible using adjuvant treatment with nivolumab.
Rob H. A. Verhoeven, Steven C. Kuijper, Marije Slingerland, Bas Wijnhoven, Mark I. van Berge Henegouwen, Peter S. N. van Rossum, Sarah Derks, Bianca Mostert, Nadia Haj Mohammad, Hanneke W. M. van Laarhoven   +9 more
wiley   +1 more source