Results 121 to 130 of about 111,421 (336)

Endoscopic ultrasound in the staging of gastrointestinal luminal malignancies [PDF]

open access: yes, 2013
Endoscopic ultrasound (EUS) is an important tool in the staging of gastrointestinal cancers. This review highlights the use of EUS in the staging of gastrointestinal luminal malignancies and compares the performance of EUS with other imaging modalities ...
Azzopardi, Neville
core  

A rare presentation of choroidal metastasis from primary esophageal adenocarcinoma successfully treated with intensity-modulated radiation therapy

open access: yesAmerican Journal of Ophthalmology Case Reports, 2018
Purpose: In this case report, we present a case of choroidal metastasis from a primary esophageal adenocarcinoma that was treated successfully with intensity-modulated radiation therapy.
Rishabh C. Date   +6 more
doaj   +1 more source

Pan‐cancer analysis reveals molecular signatures for predicting matrix stiffness in solid tumors

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Tumor matrix stiffness plays a critical role in cancer progression, metastasis, and therapy resistance. Here, the authors leveraged tumor RNA‐seq data to identify molecular signatures of mechanical properties across various cancer types and build a computational model for predicting tumor matrix stiffness.
Gongyu Tang   +6 more
wiley   +1 more source

Absence of an embryonic stem cell DNA methylation signature in human cancer. [PDF]

open access: yes, 2019
BackgroundDifferentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture
Christensen, Brock C   +5 more
core  

TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer

open access: yesiMetaOmics, EarlyView.
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin   +7 more
wiley   +1 more source

Polycyclic aromatic hydrocarbons and esophageal squamous cell carcinoma [PDF]

open access: yes, 2012
Esophageal cancer (EC) is the 8th most common cancer and the 6th most frequent cause of cancer mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common type of EC.
Dawsey, S.M.   +3 more
core  

Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro

open access: yesMolecular Cancer, 2006
Background Barrett's esophagus, a risk factor for esophageal adenocarcinoma, is associated with reflux disease. The aim of this study was to assess the expression of bile acid receptors in the esophagus (normal, esophagitis, Barrett's esophagus and ...
Frossard Jean-Louis   +10 more
doaj   +1 more source

Mitochondrial fission protein 1 in the regulation of mitochondrial quality control: A cancer perspective

open access: yesInterdisciplinary Medicine, EarlyView.
Background: Mitochondrial fission protein (FIS1), affecting energy metabolism and homeostasis, is crucial for mitochondrial quality control (MQC) and tumor progression. Key Points: It varies in expression across TME, influencing tumor progression.
Chao Wei   +7 more
wiley   +1 more source

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