New trend in molecular diagnostics: Insights from the tumor microenvironment
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan +3 more
wiley +1 more source
A phase II evaluation of high dose cisplatin and etoposide in patients with advanced esophageal adenocarcinoma [PDF]
C. Harris Spiridonidis +5 more
openalex +1 more source
Relationship between p53 expression and gastric cancers in cardia and antrum [PDF]
Background: The mutations in p53 gene and accumulation of p53 protein are the most common genetic events in gastric carcinomas. The present study was conducted to compare the frequency of p53 gene overexpression in a consecutive series of adenocarcinomas
Amiriani, T. +3 more
core
Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong +10 more
wiley +1 more source
Cigarette smoking and esophageal and gastric cardia adenocarcinoma [PDF]
Zuo‐Feng Zhang +2 more
openalex +1 more source
Pediatric autoimmune gastritis: An international, multicentric study
Abstract Objectives Autoimmune gastritis (AIG) has been poorly described in childhood. We sought to identify the patterns of manifestations of pediatric AIG at onset and to describe its laboratory, clinical, and histopathological features. Methods This was a retrospective, longitudinal, multicenter, cohort study enrolling histologically proven AIG ...
Marco Vincenzo Lenti +40 more
wiley +1 more source
Marked increase in the incidence rate of esophageal adenocarcinoma in a high-risk area for esophageal cancer [PDF]
BACKGROUND: Esophageal cancer (EC) is the eighth common cancer worldwide. Esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAD) are the most common histologic types of EC.
Ghasemi-Kebria, F. +7 more
core
Pediatric endoscopic mucosal resection: A 10‐year single‐center experience
ABSTRACT Objectives Endoscopic mucosal resection (EMR) is well established in adult gastroenterology but remains underutilized in pediatrics due to limited data, training opportunities, and equipment. This study presents a 10‐year, single‐center experience with conventional hot and cold snare EMR, band‐assisted (B‐EMR), and underwater EMR (U‐EMR ...
Brett J. Hoskins +2 more
wiley +1 more source
Mutations in β-Catenin and APC Genes are Uncommon in Esophageal and Esophagogastric Junction Adenocarcinomas [PDF]
Young Woo Choi +4 more
openalex +1 more source
ABSTRACT Endometrial cancer (EC) is one of the most prevalent gynecologic malignancies, with increasing incidence worldwide. Recent studies have highlighted the critical roles of long noncoding RNAs (lncRNAs) in regulating tumor progression. This study investigated the oncogenic function of lncRNA LINC00958 in EC and its underlying mechanism involving ...
Xia Hong, Su‐Li He
wiley +1 more source

