Results 171 to 180 of about 111,421 (336)

Disparities in Gastrointestinal Cancer Incidence in Asian American, Native Hawaiian, and Other Pacific Islander Groups

Gastro Hep Advances
Background and Aims: The Asian American, Native Hawaiian, and Other Pacific Islander (AANHPI) population are heterogeneous in health risk factors, socioeconomic status, and health outcomes.
Vicki Tang, Cynthia W. Ko
doaj   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

Integrating construction and spatial imaging of organoid for tumor metabolic heterogeneity and interactions

VIEW, EarlyView.
Enzymatically derived tissue debris (TD) is utilized to establish patient‐derived lung cancer tissue spheres (LCOs), which, in conjunction with mass spectrometry imaging, enable the investigation of tumor metabolic heterogeneity and maintenance of CSCs.
Ling Guo, Zhaohua Xia, Jiaxin Wang, Xiaoling Yu, Chuanyue Wu, Qian Luo, Chao Zhao   +6 more
wiley   +1 more source

Organoid‐based novel technology for antitumor drug screening

VIEW, EarlyView.
Organoids represent a cutting‐edge research model that closely mimics in vivo organ physiology, making them highly valuable for tumor immunotherapy drug screening. This review explores the integration of organoids with advanced technologies, such as gene editing, 3D bioprinting, and AI, highlighting novel fusion platforms and their applications.
Yu Su, Yuan Chen, Guanning Wei, Yihai Shi   +3 more
wiley   +1 more source

Laryngopharyngeal Reflux: The Impact of Obesity

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan, Mary J. Hawkshaw, Robert T. Sataloff   +2 more
wiley   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Indomethacin-Induced Apoptosis in Esophageal Adenocarcinoma Cells Involves Upregulation of Bax and Translocation of Mitochondrial Cytochrome C Independent of COX-2 Expression

, 2000
Sanjeev Aggarwal, Neelam Taneja, Lin Lin, Mark B. Orringer, Alnawaz Rehemtulla, David G. Beer   +5 more
openalex   +1 more source

Causal Relationships Between Gastroesophageal Reflux Disease and Myocardial Infarction: Insights From Univariable and Multivariable Mendelian Randomization Analyses

Annals of Human Genetics, EarlyView.
ABSTRACT Background Observational studies have indicated that gastroesophageal reflux disease (GERD) is connected to myocardial infarction (MI). Nonetheless, the question of causality in these relationships remains unresolved, given the potential influence of confounding variables.
Xiaoya Zheng, Teng Hu, Tianxiang Fang, Pengpeng Su, Yingsong Wang, Ning Huangfu   +5 more
wiley   +1 more source

Is the Incidence of Early‐Onset Adenocarcinomas in Aotearoa New Zealand Increasing?

Asia-Pacific Journal of Clinical Oncology, EarlyView.
There is a rising incidence of early‐onset adenocarcinomas in Aotearoa New Zealand which is site‐specific. This includes breast, colorectal, uterine, and prostate adenocarcinomas in the total population and colorectal, uterine, and lung adenocarcinomas in the Māori population.
Raymond Phang, Oliver Waddell, William Dixon, John Pearson, Andrew McCombie, Frank Frizelle   +5 more
wiley   +1 more source

The SORTIE trial: palliation with stent (S) or radiation therapy (RT) 20 Gy in 5 fractions intervention for esophageal cancer dysphagia: a multicenter trial for T-4, M+/- squamous or adenocarcinoma of the esophagus. a randomized trial relief from dysphagia and quality of life (QOL) analysis [PDF]

, 2002
Andrew T. Turrisi, Robert H. Hawes, Yuko Y. Palesch, Carol Redmond, Todd Williams, Carolyn E. Reed, Patrick D. Mauldin, Peter B. Cotton   +7 more
openalex   +1 more source