Personalized Cancer Vaccines in the Clinical Trial Pipeline
This study analyzes the current landscape of personalized cancer vaccine clinical trials, highlighting trends in vaccine platforms, trial phases, and geographic distribution. Peptide and dendritic cell vaccines dominate early‐stage research, with promising immune responses observed in melanoma, glioblastoma, and urothelial cancer trials.
Liudmila Iamukova, Elena Alferova
wiley +1 more source
Preoperative prevalence of Barrett's esophagus in esophageal adenocarcinoma: A systematic review [PDF]
Gareth S. Dulai +4 more
openalex +1 more source
Photoimmunotherapy (PIT) in vitro. OE19 cells formed blisters 3 h after laser illumination using adecatumumab‐IR700. ABSTRACT Near‐infrared photoimmunotherapy (NIR‐PIT) is a tumor‐specific treatment using monoclonal antibody (mAb) photosensitizer conjugates, followed by near‐infrared light irradiation.
Maasa Sasabe +14 more
wiley +1 more source
Synchronous advanced gastric adenocarcinoma and advanced esophageal squamous cell carcinoma [PDF]
Fernando A. M. Herbella +4 more
openalex +1 more source
ABSTRACT Objectives This pivotal study aimed to evaluate the performance of the CAD‐EYE prototype in identifying esophageal squamous cell carcinoma (ESCC) and gastric neoplasm (GN) for regulatory approval of the Pharmaceuticals and Medical Devices Agency in Japan.
Seiichiro Abe +13 more
wiley +1 more source
Discussion on preoperative prevalence of Barrett's esophagus in esophageal adenocarcinoma: A systemic review [PDF]
Martin Gough +4 more
openalex +1 more source
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
632. Cox-2 Promoter-Driven and Infectivity-Enhanced Adenoviral Vectors Are Promising Therapeutic Agents for Esophageal Adenocarcinoma [PDF]
openalex +1 more source
Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments
Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis +2 more
wiley +1 more source
Vascular endothelial growth factor and basic fibroblast growth factor expression in esophageal adenocarcinoma and Barrett esophagus [PDF]
Reginald V. Lord +10 more
openalex +1 more source

