This meta‐analysis of nine studies (202 patients) demonstrates that peroral endoscopic myotomy with fundoplication (POEM‐F) achieves a technical success of 94.8% and significant symptom improvement (Eckardt score reduction from 8.3 to 1.1). Post‐procedural esophagitis occurred in 20.7% and wrap integrity was preserved in 75.7% on follow‐up, supporting ...
Yusuf Kagzi +2 more
wiley +1 more source
The Interplay Between Esophageal Adenocarcinoma and Its Tumor Microenvironment: Toward Innovative Therapies. [PDF]
Fioretzaki R +8 more
europepmc +1 more source
Elevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma [PDF]
Lars M. Schiffmann +13 more
openalex +1 more source
What's New? Patients with esophageal or gastroesophageal junction (GEJ) cancer with residual disease after treatment with neoadjuvant chemoradiotherapy (nCRT) and resection frequently experience poor survival. Improvements in outcome, however, may be possible using adjuvant treatment with nivolumab.
Rob H. A. Verhoeven +9 more
wiley +1 more source
Synergistic Disruption of Survival and Metastatic Potential in Esophageal Adenocarcinoma Cells Through Combined Inhibition of HIF1α and CD73. [PDF]
Mersich I +6 more
europepmc +1 more source
Genomic regions associated with susceptibility to Barrett\u27s esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study [PDF]
et al.,, Nalbantoglu, Ilke, Wang, Jean S
core +1 more source
Diabetes in relation to Barrett’s esophagus and adenocarcinomas of the esophagus: A pooled study from the International Barrett’s and Esophageal Adenocarcinoma Consortium [PDF]
Jessica L. Petrick +20 more
openalex +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Impact of Alpha-mangostin on human esophageal adenocarcinoma cells reveals activation of key apoptotic signaling pathways. [PDF]
Canary C +6 more
europepmc +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source

