Results 261 to 270 of about 111,421 (336)

A case report of Barrett's esophageal adenocarcinoma in a young adult aged 20 years. [PDF]

DEN Open
Ohi T, Sasaki F, Maeda N, Uehara S, Maeda H, Tanaka A, Kanmura S, Yamasuji A, Ido A.   +8 more
europepmc   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

Advanced Therapeutics, Volume 8, Issue 10, October 2025.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam, Lu Yanjun, Bee Luan Khoo, Tongxu Si, Heng Zou, Mengsu Yang   +5 more
wiley   +1 more source

Metabolic Profiling of Distinct <i>TP53</i>-Mutant Esophageal Adenocarcinoma Models Reveals Different Bioenergetic Dependencies. [PDF]

Int J Mol Sci
Cataldi-Stagetti E, Rizzardi N, Orsini A, De Nicolo B, Diquigiovanni C, Pincigher L, Moruzzi N, Fato R, Bergamini C, Bonora E.   +9 more
europepmc   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, Volume 12, Issue 39, October 20, 2025.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinoma. [PDF]

Nat Cancer
Barroux M, Househam J, Lakatos E, Ronel T, Baker AM, Salié H, Mossner M, Smith K, Kimberley C, Nowinski S, Berner A, Gunasri V, Borgmann M, Liffers S, Jansen M, Caravagna G, Steiger K, Slotta-Huspenina J, Weichert W, Zapata L, Giota E, Lorenzen S, Alberstmeier M, Chain B, Friess H, Bengsch B, Schmid RM, Siveke JT, Quante M, Graham TA.   +29 more
europepmc   +1 more source

GSTM1, GSTT1, GSTP1 and CYP1A1 genetic polymorphisms and susceptibility to esophageal cancer in a French population: Different pattern of squamous cell carcinoma and adenocarcinoma

, 2004
Ahmed Abbas
openalex   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, Volume 12, Issue 38, October 13, 2025.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Is it time to retire preoperative radiation for localized esophageal and gastro-esophageal adenocarcinoma? [PDF]

Oncologist
Pabon CM, Spieler B, Li JJ, Ajani J, Hosein PJ, Blum Murphy M.   +5 more
europepmc   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 38, October 13, 2025.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source