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Patient-derived esophageal adenocarcinoma organ chip: a physiologically relevant platform for functional precision oncology

Pal S, Shimshoni E, Torres SF, Kong M, Tai K, Sangwan V, Bertos N, Bérubé J, Bailey SD, Ingber DE, Ferri L.   +10 more
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Epidemiology of esophageal adenocarcinoma

Journal of Surgical Oncology, 2005
AbstractThe incidence of esophageal adenocarcinoma has risen rapidly over the past 25 years in the United States as well as in several Western European countries. This increase had been most dramatic among white males. The majority of these cancers arise from a background of premalignant Barrett esophagus.
Manuel, Pera, Carlos, Manterola, Oscar, Vidal, Luis, Grande   +3 more
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Radiotherapy for Esophageal Adenocarcinoma

2018
Adenocarcinomas occur in distal esophagus and often involve esophagogastric junction. Radiotherapy plays a key role in treatment, often in combination with chemotherapy and surgery in multi-modalities management. For resectable esophageal primaries, neoadjuvant chemoradiotherapy plus surgery can downstage disease and improve outcome over surgery alone.
Dora L W, Kwong, K O, Lam
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Chemotherapy for Esophageal Adenocarcinoma

2018
Esophageal and esophagogastric junction adenocarcinoma is a distinct entity from esophageal squamous cell carcinoma with respect to etiology and biology despite sharing the same anatomical location. While most international treatment guidelines recommend a similar management strategy for both esophageal squamous and adenocarcinoma histologies, the ...
Ka-On, Lam, Dora L W, Kwong
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Esophageal Adenocarcinoma: Pseudo-Nutcracker Esophagus

Dysphagia, 2008
Pseudoachalasia due to adenocarcinoma is well known. We report a case of nutcracker esophagus in the setting of outflow obstruction from esophageal adenocarcinoma. Endoscopy is warranted to exclude similar lesions in patients with "pseudo-nutcracker esophagus".
Adeyemi, Lawal, Stephen, Antonik, Kulwinder, Dua, Benson T, Massey   +3 more
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ERBB2 Amplifications in Esophageal Adenocarcinoma

The Annals of Thoracic Surgery, 2004
ERBB2 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, Her-2-neu) gene amplification and overexpression has been reported in several types of cancer. The purpose of this study was to (1) determine the frequency of ERBB2 amplification (in comparison to other proto-oncogenes) in tumors from patients with esophageal adenocarcinoma, (2 ...
Peter S, Dahlberg, Blake A, Jacobson, Ganesh, Dahal, James M, Fink, Robert A, Kratzke, Michael A, Maddaus, Lance J, Ferrin   +6 more
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Staging esophageal adenocarcinoma.

Seminars in gastrointestinal disease, 2004
The incidence of esophageal adenocarcinoma has increased dramatically in Western societies over the last 20 years. Most patients present with advanced disease. Stage-dependent treatment protocols require the most complete and accurate staging possible.
Ian F, Yusoff, Anand V, Sahai
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Barrett's Esophagus and Esophageal Adenocarcinoma

Gastroenterology Clinics of North America, 1991
Barrett's esophagus is a condition in which the normal stratified squamous epithelium is replaced by a specialized metaplastic columnar epithelium. It develops as a consequence of chronic gastroesophageal reflux and predisposes to the development of esophageal adenocarcinoma.
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