Results 201 to 210 of about 266,260 (301)

Development of Second Primary Malignancies in Long-term Survivors of Unresectable Esophageal Cancer. [PDF]

Cancer Diagn Progn
Watanabe R, Mitani S, Okura M, Inagaki C, Tanizaki J, Tanaka K, Iwasa T, Yonesaka K, Hayashi H.   +8 more
europepmc   +1 more source

The Predictive Value of the Tumor‐Stroma Ratio for Neoadjuvant Endocrine Therapy in Hormone Receptor‐Positive Breast Cancer

International Journal of Cancer, EarlyView.
Neoadjuvant endocrine therapy (NET) can help prevent metastases and improve survival in patients with hormone receptor‐positive (HR+) breast cancer. Identifying which HR+ patients will benefit from NET, however, remains challenging. Here, in a patient cohort in the Netherlands, the authors evaluated tumor‐stroma ratio (TSR) and magnetic resonance ...
Layla Andour, Sophie C. Hagenaars, Anne Florine de Groot, Elly M. M. Krol‐Warmerdam, Judith R. Kroep, Hans Marten Hazelbag, Gerrit‐Jan Liefers, Marieke E. Straver, Wilma E. Mesker   +8 more
wiley   +1 more source

Long-term trends in disease burden of esophageal cancer in China and the forecast until 2050. [PDF]

BMC Gastroenterol
Huang X, Sang Z, Shi Z, Li J, Geng M, Cao X.   +5 more
europepmc   +1 more source

Targeting DGKα/PA axis inhibits tumor immune evasion and augments sensitivity to immunotherapy in gastrointestinal cancers

iMeta, EarlyView.
Immune checkpoint inhibitors (ICIs) have shown promising antitumor efficacy in certain types of solid tumors. However, the efficacy of ICIs remains unsatisfactory owing to the dysregulation of signaling pathways in local tumor tissues. Here, we reveal that diacylglycerol kinase α (DGKα)‐derived phosphatidic acid (PA) directly binds to nuclear factor‐κB
Jie Chen, Siqi Liu, Ting Peng, Fenglong Wang, Yuheng Zhu, Jingyuan Pang, Qingnan Wu, Yan Wang, Qimin Zhan   +8 more
wiley   +1 more source

WTAP stabilizes MMP12 expression to promote the malignant phenotypes of esophageal cancer cells. [PDF]

Regen Ther
Zhao M, Zhang H, Han X, Wei Y, Zhang M, Hu B, Lv T, Zhang G.   +7 more
europepmc   +1 more source

Intratumoral Enterobacter hormaechei drives gemcitabine resistance in pancreatic cancer via cddL‐mediated drug inactivation

iMeta, EarlyView.
Gemcitabine resistance poses a critical barrier to improving survival in pancreatic cancer, yet the microbial drivers remain elusive. By integrating 16S rRNA amplicon sequencing with large‐scale culturomics across 114 clinical samples, we identified Enterobacter hormaechei as a key intratumoral pathogen. We demonstrate that E.
Jun‐Feng Peng, Meixia Li, Ting Niu, Judong Li, Wei Niu, Minghui Zheng, Quanjiang Ji, Chuan Li, Chenghao Shao, Kan Ding   +9 more
wiley   +1 more source

Managing Esophageal Cancer

Cancer Control, 1999
openaire   +2 more sources

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Dosimetric impact of endoscopic titanium clips in photon and proton radiotherapy for esophageal cancer. [PDF]

Front Oncol
Siah N, Wang X, Li X, Qi P, Wang B, Zhou R, Yu C, Han J, Dong X, Zhang S.   +9 more
europepmc   +1 more source