Results 221 to 230 of about 177,438 (306)

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

open access: yesInterdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu   +6 more
wiley   +1 more source

Relative Contributions of Gastrointestinal‐Specific Hypervigilance and Anxiety in Explaining Eating Disorder Symptoms

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objective Gastrointestinal (GI) disturbances and eating disorder symptoms commonly co‐occur. Hypervigilance and anxiety about GI symptoms may motivate eating disorder behaviors to manage and/or avoid GI symptoms. We hypothesized that GI‐specific anxiety would be more strongly associated with dietary restriction and purging than GI‐specific ...
Gabriella Pucci   +6 more
wiley   +1 more source

Independent Prognostic Value of Natural Tooth Count Versus Posterior Teeth Occlusion in Resected Pancreatic Cancer

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Prognostic significance of preoperative patient‐related factors, including oral health status, in pancreatic ductal adenocarcinoma (PDAC) remains unclear. We evaluated the association between preoperative factors—particularly oral health parameters—and long‐term survival after curative PDAC resection.
Kaoru Seo   +8 more
wiley   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund   +23 more
wiley   +1 more source

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