Results 41 to 50 of about 163,250 (350)

Esophageal reconstruction for complex benign esophageal disease

The Journal of Thoracic and Cardiovascular Surgery, 1990
We report the cases of 35 patients with complex benign esophageal disease who required radical surgical reconstruction. These patients had undergone 63 previous esophageal operations. Twenty-seven patients required esophagogastrectomy, four had esophageal exclusion before colon interposition, two had cardioplasty, and two without stricture did not ...
Ellis Fh, Gibb Sp
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Differential Contributions of Fibroblast Subpopulations to Intercellular Communication in Eosinophilic Esophagitis

Biology
Fibroblast heterogeneity remains undefined in eosinophilic esophagitis (EoE), an allergic inflammatory disorder complicated by fibrosis. We utilized publicly available single-cell RNA sequencing data (GSE201153) of EoE esophageal biopsies to identify ...
Tao Li, Matthew Salomon, Ling Shao, Atousa Khalatbari, Joshua D. Castle, Anisa Shaker   +5 more
doaj   +1 more source

Surgical treatment of Killian‐Jamieson diverticulum: A case report and literature review

Clinical Case Reports, 2019
Key Clinical Message This study describes a patient with symptomatic Killian‐Jamieson, a rare entity, successfully treated by cervical approach with diverticulum resection and esophagomyotomy.
Vagner Birk Jeismann, Edno Tales Bianchi, Sérgio Szachnowicz, Francisco Carlos Bernal da Costa Seguro, Francisco Tustumi, Andre Fonseca Duarte, Rubens Antonio Aissar Sallum, Ivan Cecconello   +7 more
doaj   +1 more source

Gastro Esophageal Reflux Diseases Pada Ibu Rumah Tangga Dewasa Muda Dengan Stressor Financial Keluarga [PDF]

, 2013
Latar Belakang. Gastro-oesophageal reflux disease ( GERD ) adalah salah satu kelainan yang sering dihadapi di lapangan dalam bidang gastrointestinal. Pervalensi GERD di asia sekitar 2-5 % dengan sekitar 50 % pasien gerd bersifat simptomatik.
Supriyatin, J. (Jayanti)
core  

Body Mass Index, Smoking, and Alcohol and Risks of Barrett’s Esophagus and Esophageal Adenocarcinoma: A UK Prospective Cohort Study [PDF]

, 2014
BACKGROUND: The timing of the risk factors cigarette smoking, alcohol and obesity in the development of Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) is unclear.
Cheong, Edward, Fitzgerald, Rebecca, Hart, Andrew, Igali, Laszlo, Khaw, Kay-tee, Luben, Robert, Yates, Max   +6 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Joint Disease Mapping of Two Digestive Cancers in Golestan Province, Iran Using a Shared Component Model [PDF]

, 2015
Objectives: Recent studies have suggested the occurrence patterns and related diet factor of esophagus cancer (EC) and gastric cancer (GC). Incidence of these cancers was mapped either in general and stratified by sex.
Chamanpara, P., Faradmal, J., Moghimbeigi, A., Poorolajal, J.   +3 more
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Gastroesophageal reflux disease and tooth erosion [PDF]

, 2011
The increasing prevalence of gastroesophageal reflux disease (GERD) in children and adults, and of “silent refluxers” in particular, increases the responsibility of dentists to be alert to this potentially severe condition when observing unexplained ...
Kaidonis, J., Ranjitkar, S., Smales, R.
core   +4 more sources