Results 41 to 50 of about 120,357 (292)

Esophageal Potential Difference Measurements in Esophageal Disease

Gastroenterology, 1982
To determine if esophageal transmural electrical potential difference measurements are of use for evaluating esophageal disease, we recorded potential difference in 129 patients with one or more of the following: heartburn, dysphagia, and chest pain.
R C, Orlando, D W, Powell, J C, Bryson, H B, Kinard, C N, Carney, J D, Jones, E M, Bozymski   +6 more
openaire   +2 more sources

Introduction: Esophageal Adenocarcinoma: Updates of Current Status

, 2018
Esophageal and esophagogastric adenocarcinoma is highly prevalent in the Western populations and is a major cause of cancer-related morbidity and mortality worldwide. The incidence of esophageal adenocarcinoma is rapidly rising in the Western populations.
Lam, AK, Lam, Alfred, Alfred K. Lam
core   +1 more source

Transient Loss of Esophageal Striated Muscle Contractility After Cricopharyngeal Botulinum Toxin Injection for Retrograde Cricopharyngeal Dysfunction [PDF]

Gastro Hep Advances
Anisa Shaker, Karla O’Dell, Edy Soffer
doaj   +2 more sources

Increasing Social Vulnerability Impacts Presentation and Decreases Treatment Response in Eosinophilic Esophagitis

Gastro Hep Advances
Background and Aims: Social vulnerability describes relative disadvantage according to demographics, socioeconomic status, and resources. The impact of social vulnerability on eosinophilic esophagitis (EoE) remains unknown.
Angelica R. Mirzoca, Stefani Aleman, Alexandra A. Weir, Sean S. LaFata, Timothy S. Gee, Arjun K. Juneja, Hannah L. Thel, Brenderia A. Cameron, Justin McCallen, Christopher J. Lee, Gustaf N. Hendrick, Jose C. Bermudez, Daniel Song, Walker D. Redd, Trevor S. Barlowe, Cary C. Cotton, Craig C. Reed, Evan S. Dellon   +17 more
doaj   +1 more source

Weight Gain Is Associated With Decreased Treatment Response to Dietary Therapy in Adults With Eosinophilic Esophagitis

Gastro Hep Advances
Background and Aims: Dietary therapy is a first-line treatment for eosinophilic esophagitis (EoE). We aimed to determine whether dietary therapy treatment outcomes vary by baseline weight status or change in body weight during treatment. Methods: In this
Stephanie A. Borinsky, Sean S. LaFata, Timothy S. Gee, Hannah L. Thel, Brenderia A. Cameron, Angela Z. Xue, Akshatha Kiran, Adolfo A. Ocampo, Justin McCallen, Christopher J. Lee, Walker D. Redd, Trevor S. Barlowe, Rayan N. Kaakati, Cary C. Cotton, Swathi Eluri, Craig C. Reed, Evan S. Dellon   +16 more
doaj   +1 more source

Autophagy and its current relevance to the diagnosis and clinical management of esophageal diseases.

, 2016
Autophagy is an evolutionarily conserved cell survival program that degrades dysfunctional organelles and misfolded or long-lived proteins through the formation of lysosomes.
Streutker, Catherine J, Swanson, Paul E, Langer, Rupert   +2 more
core   +1 more source

Spontaneous circumferential intramural esophageal dissection complicated with esophageal perforation and esophageal-pleural fistula: a case report and literature review

, 2016
© 2014 International Society for Diseases of the Esophagus Spontaneous intramural esophageal dissection (IED) is a rare disease entity. There are few reports of spontaneous IED requiring surgical treatment.
Tam, G, Law, TT, Tong, DKH, Zhu, RY, Law, SYK   +4 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source