Results 61 to 70 of about 29,789 (214)

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Plotting the Path to Recovery: Group‐Based Trajectory Modelling of Physical Activity After Major Oncological Surgery to Predict Postoperative Outcomes

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Methods The role of early and increased activity on postoperative recovery is well established, yet the impact of its day‐to‐day variability remains unclear. This retrospective cohort study examined associations between early in‐hospital postoperative physical activity trajectories and postoperative outcomes among 218 surgical ...
Ella Jansen, Carlos de Miguel Llorente, Petra Bor, Jan Willem van den Berg, Karin Valkenet   +4 more
wiley   +1 more source

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source

Standardized Reporting of Cardiac Magnetic Resonance Examinations in Children With Cardiac Diseases and Adults With Congenital Heart Disease: A Scientific Statement From the Association for European Pediatric and Congenital Cardiology (AEPC) and the International Society for Magnetic Resonance in Medicine (ISMRM)

Journal of Magnetic Resonance Imaging, EarlyView.
Francesca Raimondi, Inga Voges, Lamia Ait‐Ali, Sonya Babu‐Narayan, Rene Botnar, Barbara Burkhardt, Adrienne Campbell‐Washburn, Dominik Daniel Gabbert, Georg Hansmann, Willem A. Helbing, Hasan Hosan, Sylvia Krupickova, Heiner Latus, Duarte Martins, Colin McMahon, Christian Meierhofer, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Claudia Prieto, Milan Prsa, Kuberan Pushparajah, José F. Rodríguez Palomares, Samir Sarikouch, Lars Grosse‐Wortman, F. Gerald Greil, Heynric Grotenhuis   +26 more
wiley   +1 more source

DARS2 Promotes Tumorigenesis and Metastasis by Activating PI3K/Akt/GSK‐3β/β‐Catenin Signaling Pathway in Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Aspartyl‐tRNA synthetase 2 (DARS2), the mitochondrial enzyme responsible for aminoacylation of aspartyl‐tRNA, is traditionally known for its effect on protein synthesis. Recently, DARS2 is reported to be implicated in tumorigenesis. However, its specific effect on breast cancer (BC) is poorly understood.
Na Wang, Ming Huang
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

The Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen, Carmen Esna, Camille Prigent, Anna Miles   +3 more
wiley   +1 more source

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

The Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar, Eric Allen, Yun‐Lun Liu, Alexandra D. D'Oto, Rishi Suresh, Adrianna Shembel, Ted Mau   +6 more
wiley   +1 more source

Cervical Inlet Patches in R‐CPD: An Unrecognized Predictor of Treatment Failure

The Laryngoscope, EarlyView.
This retrospective cohort study identified cervical inlet patches (CIP) in 19.8% of patients undergoing cricopharyngeal botulinum toxin injection for R‐CPD. CIP presence and increasing age independently predicted failure to sustain a long‐term treatment response, suggesting that CIP may be an underrecognized factor in R‐CPD treatment durability ...
Andrew Geoffrey Tritter, Nabeeha Hasan, Jered Wilson   +2 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source