Results 211 to 220 of about 27,147 (278)

Radiogenomics: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 2, February 2026.
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang, Qingpei Lai, Jin Cao, Jerry Chi Fung Ching, Xinzhi Teng, Jiang Zhang, Shara Wee Yee Lee, Ge Ren, Jing Cai   +8 more
wiley   +1 more source

Submucosal Tunneling Muscle Biopsy for Esophageal Motility Disorders: A Case Report. [PDF]

Clin Endosc, 2020
Smirnov AA, Kiriltseva MM, Burakov AN, Maksimov MV, Botina AV, Saadulaeva MM, Konkina NV.   +6 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Surgical and per-oral endoscopic myotomy (POEM) for the treatment of primary esophageal motility disorders: A systematic analysis of current trends in Germany between 2011 and 2019. [PDF]

PLoS One
Kandler J, Essing T, Schöler D, Flügen G, Knoefel WT, Roderburg C, Luedde T, Loosen SH.   +7 more
europepmc   +1 more source

Alcohol Use After TIPS Implantation Significantly Increases the Risk of ACLF and Liver‐Related Death

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Complications related to portal hypertension (PH) in patients with alcohol‐related liver disease (ALD) can be controlled by transjugular intrahepatic portosystemic shunt (TIPS) placement; however, the impact of ongoing alcohol use (AU) after TIPS remains scarcely investigated.
Caroline Schwarz, Andrea Kornfehl, Reema Abid, Theresa Müllner‐Bucsics, Julia Kappel, Michael Schwarz, Benedikt S. Hofer, Nina Dominik, Georg Kramer, Benedikt Simbrunner, Mathias Jachs, Lukas Reider, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Lukas Hartl   +15 more
wiley   +1 more source

Brain lesion extent, growth, and body composition in children with cerebral palsy

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 199-210, February 2026.
Abstract Aim To investigate the relationship between growth, body composition, and the extent of brain lesion measured using structural magnetic resonance imaging (MRI) in children with cerebral palsy (CP). Method This prospective population‐based cohort study recorded 359 assessments from 124 children with CP aged 18 months to 13 years (38% female ...
Stina Oftedal, Simona Fiori, Kristie L. Bell, Katherine A. Benfer, Leanne Sakzewski, Robert S. Ware, Peter S. W. Davies, Roslyn N. Boyd   +7 more
wiley   +1 more source

Effectiveness and safety of abobotulinumtoxinA in pediatric lower limb spasticity: A phase IV, prospective, observational, multicenter study

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 227-239, February 2026.
Abstract Aim To assess the longitudinal attainment of patient‐centered, function‐related Goal Attainment Scaling Total (GAS T)‐score after repeated abobotulinumtoxinA (AboBoNT‐A) injections over a period of up to 30 months and up to 10 cycles. Method In this prospective observational study, the investigators' clinical practices recruited patients aged ...
Mark E. Gormley, Edward Dabrowski, Mauricio R. Delgado, Ann Tilton, Asare Christian, Sarah Helen Evans, Anne‐Sophie Grandoulier, Jumaah Goldberg   +7 more
wiley   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
HOXB4 is overexpressed in bladder cancer and associated with poor prognosis. By transcriptionally activating Smoothened (SMO), HOXB4 amplifies SMO–GLI signaling to promote tumor growth and metastatic behavior. This graphical abstract highlights the HOXB4–SMO axis as a key driver of bladder cancer progression and a potential target for future ...
Zhaoheng Jin, Wenjie Yang, Yueqiang Peng, Lin Ma, Ziyi Li, Jie Dong, Zhigang Ji   +6 more
wiley   +1 more source