Results 101 to 110 of about 126,956 (339)

Giant fibrovascular polyp of esophagus

Journal of Digestive Endoscopy, 2016
Benign tumors of esophagus are uncommon and account for only 3% of all esophageal neoplasms. Fibrovascular polyps (FVP) are rare intraluminal tumors of esophagus.
Ramakanth Sannidi, Shravan Kumar Porika, Umadevi Malladi, Ramanna Macherla   +3 more
doaj   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Evaluation of the quality of life in patients with esophageal cancer treated with self-expanding stent

Archivo Médico de Camagüey, 2018
Background: the study of health-related quality of life in patients with inoperable esophageal cancer using self-expanding stent provides useful information for selecting the appropriate treatment option.
Yanet Ortega-Dugrot, Elizabeth Montes-de-Oca-Megías, Mildred Cecilia Armenteros-Torres, Norberto Caridad Alfonso-Contino, Jorge Luis García-Menocal-Hernández, Enrique Olazabal-García   +5 more
doaj  

Unusual metastasis of esophageal cancer [PDF]

, 2014
Introduction. Carcinoma of the esophagus is in the eighth place by the frequency of malignant diseases and the sixth cause of death from cancer worldwide. It usually metastasizes to regional lymph nodes, liver, lungs, central nervous system, and
Bogdanović Bogdan, Kukić Biljana, Nikolić Ivan, Petrović Nemanja, Samardžija Golub, Vidović Vladimir, Vukojević Jelena   +6 more
core   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Transendoscopic laser ablation of an esophageal plasma cell tumor in a cat

Journal of Feline Medicine and Surgery Open Reports
Case summary A 15-year-old male castrated domestic shorthair cat was presented for acute lethargy, vomiting and hyporexia. Abdominal and thoracic radiographs revealed a caudal thoracic/esophageal soft tissue opacity with concern for an esophageal mass or
Maya E Wallick, Matthew J Lechner, Nicole C Bonaventura   +2 more
doaj   +1 more source

Sarcoma sinovial primário do esôfago

Revista do Colégio Brasileiro de Cirurgiões
Synovial sarcomas are uncommon malignant mesenchymal tumors occurring mainly near the joints of the extremities of young adults. Synovial sarcomas are exceedingly rare neoplasms of the digestive tract.
Mário Henrique Leite de Alencar, Domingos Boldrini, Aluysio de Mendonça Costa, Antônio Talvane Torres de Oliveira, Cyomara Sanches Attab   +4 more
doaj   +1 more source

Endoscopic and Oncologic Outcomes of Endoscopic Resection for Superficial Esophageal Neoplasm

Gut and Liver, 2015
Endoscopic resection (ER) of superficial esophageal neoplasm (SEN) is a technically difficult procedure. We investigated the clinical outcomes of ER for SEN to determine its feasibility and effectiveness.Subjects who underwent ER for SEN at Asan Medical Center between December 1996 and December 2010 were eligible.
Eun Jeong Gong, Mi Young Kim, Ji Yong Ahn, Kwi Sook Choi, Young Su Park, Jin-Ho Kim, Jeong Hoon Lee, Seunghee Baek, Do Hoon Kim, Kee Don Choi, Ho June Song, Ji Young Choi, Gin Hyug Lee, Hwoon-Yong Jung   +13 more
openaire   +5 more sources

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source