Results 111 to 120 of about 561,228 (312)

Esophageal Squamous Cell Carcinoma Patients Have an Increased Risk of Coexisting Colorectal Neoplasms

Gut and Liver, 2016
Background/Aims Esophageal squamous cell carcinoma (ESCC) and colorectal neoplasms (CRNs) share risk factors. We aimed to investigate whether the CRN risk is increased in ESCC patients.
M. Baeg, Myung-Gyu Choi, Y. Jung, S. Ko, C. Lim, Hyung Hun Kim, J. Kim, Y. Cho, J. Park, I. Lee, Sang-Woo Kim   +10 more
semanticscholar   +1 more source

A Super‐Enhancer‐Driven Transcriptional Regulatory Circuit Underlying Abiraterone Resistance in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
This study identifies a super‐enhancer‐driven transcriptional regulatory circuit comprising BCL6, SMAD3, and NFIB that cooperate to drive cholesterol synthesis via SREBF2/HMGCR/FDFT1 activation and regulate CDK2/CCND3 for cell cycle control. Targeting this circuit with BI‐3802 or downstream inhibitors (Fatostatin/Lovastatin) overcomes abiraterone ...
Liling Jiang, Jiamin Wang, Guanjie Peng, Haichuan Zhang, Jinxin Fang, Yingyin Gao, Enzhe Lou, Yangzhou Liu, Wa Ding, Bingyuan Liu, Qiong Mao, Lizhen Jiang, Aochu Liu, Xinyue Li, Shiwen Hu, Qiaomin Ma, Yueyuan Zheng, Zhigang Zhao, Xianping Shi   +18 more
wiley   +1 more source

Clinical Outcomes of Endoscopic Submucosal Dissection for Early Esophageal Squamous Cell Neoplasms: A Retrospective Single-Center Study in China

Gastroenterology Research and Practice, 2016
Aims. To retrospectively analyze the clinical outcomes for a large number of endoscopic submucosal dissections (ESDs) in early esophageal squamous cell neoplasms (ESCNs) at the First Affiliated Hospital of Nanjing Medical University. Patients and Methods.
Yanfang Chen, Ye Zhao, Xiaojing Zhao, Ruihua Shi   +3 more
semanticscholar   +1 more source

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

Risk factors of postoperative stricture after endoscopic submucosal dissection for superficial esophageal neoplasms: A meta-analysis. [PDF]

Medicine (Baltimore), 2021
Lin N, Lin J, Gong J.
europepmc   +1 more source

Simplified criteria for diagnosing superficial esophageal squamous neoplasms using Narrow Band Imaging magnifying endoscopy

World Journal of Gastroenterology, 2016
AIM To simplify the diagnostic criteria for superficial esophageal squamous cell carcinoma (SESCC) on Narrow Band Imaging combined with magnifying endoscopy (NBI-ME). METHODS This study was based on the post-hoc analysis of a randomized controlled trial.
A. Dobashi, K. Goda, N. Yoshimura, T. Ohya, Masayuki Kato, K. Sumiyama, M. Matsushima, S. Hirooka, M. Ikegami, H. Tajiri   +9 more
semanticscholar   +1 more source

Endoscopic submucosal dissection for superficial esophageal squamous cell neoplasms

World Journal of Gastrointestinal Pathophysiology, 2012
Endoscopic resection is an effective treatment for non-invasive esophageal squamous cell neoplasms (ESCNs). Endoscopic mucosal resection (EMR) has been developed for small localized ESCNs as an alternative to surgical therapy because it shows similar effectiveness and is less invasive than esophagectomy.
Kuniomi Honda, Hirotada Akiho
openaire   +3 more sources

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

Advanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao, Jiawei Zhou, Chen‐Chen Wang, Zong‐Hao Wang, Nian‐Dong Mao, Meng‐Lan He, Peng‐Peng Zhang, Ping Huang, Guo‐Wei Ye, Yu‐Qing Zhang, Feng‐Hui Tang, Hang Zhang, Tian Xie, Xiang‐Yang Ye   +13 more
wiley   +1 more source

Esophageal Squamous Cell Carcinoma with Pancreatic Metastasis: A Case Report [PDF]

Acta Medica Iranica, 2011
Malignant tumors of pancreas are usually primary neoplasms and pancreatic metastases are rare findings. We are reporting a case of squamous cell carcinoma (SCC) of the esophagus with pancreatic metastasis.
Maryam Hassan Esfehani, Habibollah Mahmoodzadeh, Abbas Alibakhshi, Farinaz Safavi   +3 more
doaj   +1 more source

Fistula aorto-esofágica en un paciente con cáncer de esófago

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
La fistula aorto-esofágica es una complicación infrecuente del cáncer de esófago, pero extremadamente agresiva. Se presenta un paciente fumador, bebedor ocasional, que ingresa por disnea intensa, tos con expectoración, disfagia y síntomas generales que ...
Alfredo Enrique Arredondo Bruce, Elsa C. Piñero Perez, Luz Maria Cuenca Alvarez   +2 more
doaj