Patient‐derived xenograft models in pan‐cancer: From bench to clinic
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li+5 more
wiley +1 more source
Simultaneous concurrent chemoradiotherapy and esophagectomy for synchronous head and neck and esophageal squamous cell carcinoma: a retrospective review. [PDF]
Huang YM+9 more
europepmc +1 more source
Advanced single‐cell RNA sequencing in tumor immunology
This review highlights the applications of advanced single‐cell RNA sequencing (scRNA‐seq) technologies in tumor immunology. It summarizes representative scRNA‐seq methods according to technical principles, with a focus on single‐cell T cell receptor sequencing. This review also discusses how scRNA‐seq is used to construct immune cell atlases of tumors,
Yilong Liu+8 more
wiley +1 more source
Proton Pump Inhibitor Use Following Esophageal Variceal Ligation and Its Impact on Clinical Outcomes: Real-World Data from the TriNetX Global Collaborative Network. [PDF]
Amin N+4 more
europepmc +1 more source
Serum Circ‐DLGAP4 and miR‐9 as Potential Biomarkers in Pancreatic Cancer
Pancreatic cancer remains one of the malignancies characterized by the most insidious onset and dire prognosis. Preliminary diagnostic biomarkers are essential for timely identification and improved prognosis. Circ‐DLGAP4 and miR‐109 are intriguing, easily accessible genetic indicators for numerous diseases.
Marwa A. Ali+13 more
wiley +1 more source
Review of the role of submucosal injection materials in digestive endoscopy. [PDF]
Wu D+5 more
europepmc +1 more source
The objective was to identify sentinel lymph nodes (SLN) in cervical or vulvar cancer subjects scheduled for surgery using lymphosonography. Comparing surgically excised SLNs with lymphosonography showed 10 out of 11 SLNs (or 91%) were identified by lymphosonography. Lymphosonography identified all benign SLNs and 2 out of 3 malignant SLNs.
Priscilla Machado+5 more
wiley +1 more source
Gastroesophageal disease risk and inhalational exposure a systematic review and meta-analysis. [PDF]
Kim DH+7 more
europepmc +1 more source
ABSTRACT Background/Purpose The remnant stomach after distal gastrectomy (DG) which receives its blood supply mainly from the splenic artery (SPA), is at high risk for gastric ischemia following distal pancreatectomy (DP). We investigated the risk factors for ischemic necrosis of the remnant stomach (INS) during or after DP in DG patients.
Takashi Kishi+9 more
wiley +1 more source
Diagnosis and management of reactive infectious mucocutaneous eruption
Abstract Medicine's clinical understanding of reactive infectious mucocutaneous eruption (RIME) has evolved over time. It was previously described as Mycoplasma pneumoniae‐induced rash and mucositis (MIRM), and before that as a variant of Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis. Here, we summarize the current understanding of best practices
Nicole Damari+2 more
wiley +1 more source