Integrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome
What's New? Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.
Minta Kärkkäinen +9 more
wiley +1 more source
Body height and the excess cancer risk in men
What's New? In cancers that affect both sexes, men usually have a higher risk than women. While this is often attributed to behavioral factors, such as exposure to environmental carcinogens, there may be an intrinsic biological mechanism involved. Tall stature has been associated with increased cancer risk.
Cecilia Radkiewicz +6 more
wiley +1 more source
A rare case report of esophageal neuroendocrine carcinoma mimicking a submucosal tumor: Diagnosis confirmed by endoscopic ultrasound-guided fine-needle aspiration. [PDF]
Hu C, Zhu D, Li P, Ye X, Chen Z.
europepmc +1 more source
What's New? While radiotherapy is an essential component of oncology treatment, it remains unclear how the quality of life of treated patients compares to that of the general population. This pooled secondary analysis of two cross‐sectional studies conducted in Germany reveals existing gaps in global quality of life between the general population and ...
Alexander Fabian +16 more
wiley +1 more source
PATTERNS OF ESOPHAGEAL NEOPLASMS IN A REFERRAL DIAGNOSTIC CENTRE OF BANGALORE
Zubair Hasan, N. Jayaram, Uma Devi
openalex +1 more source
What's New? Patients with esophageal or gastroesophageal junction (GEJ) cancer with residual disease after treatment with neoadjuvant chemoradiotherapy (nCRT) and resection frequently experience poor survival. Improvements in outcome, however, may be possible using adjuvant treatment with nivolumab.
Rob H. A. Verhoeven +9 more
wiley +1 more source
Endoscopic submucosal tunnel dissection for large superficial esophageal squamous cell neoplasms
Yaqi Zhai
openalex +1 more source
Pan‐cancer analysis reveals molecular signatures for predicting matrix stiffness in solid tumors
What's New? Tumor matrix stiffness plays a critical role in cancer progression, metastasis, and therapy resistance. Here, the authors leveraged tumor RNA‐seq data to identify molecular signatures of mechanical properties across various cancer types and build a computational model for predicting tumor matrix stiffness.
Gongyu Tang +6 more
wiley +1 more source
Endoscopic Submucosal Dissection for Gastroesophageal Reflux Disease-Related Neoplasms. [PDF]
Chen Z +9 more
europepmc +1 more source
TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin +7 more
wiley +1 more source

