Results 261 to 270 of about 129,621 (342)

Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m6A‐YTHDF2‐dependent mechanism

iMeta, EarlyView.
Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu, Li‐Ting Chen, Xu‐Ying Pei, Shao‐Nan Hu, Fang‐Fang Zhuo, Ze‐Kun Chen, Yang Liu, Jing‐Kang Wang, Ji‐Chao Zhang, Qi Cao, Ling Li, Jing Wang, Tian‐Tian Wei, Bo Han, Peng‐Fei Tu, Xiang‐Yu Zhao, Ruidong Xue, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Concurrent esophageal squamous cell carcinoma with gastric mucosa-associated lymphoid tissue lymphoma: a case report. [PDF]

Front Oncol
Xu T, Luo S.
europepmc   +1 more source

Contrast‐Enhanced MR Fingerprinting With Delta‐Relaxometry: Investigating a New Avenue for Tumor Characterization

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI contrast agents enhance lesion characterization by altering tissue relaxation properties. However, quantitative assessment of contrast enhancement is limited by variability in contrast administration parameters, and lack of efficient and precise contrast concentration independent relaxivity (r1, r2) measurement techniques.
Shengwen Deng, Walter Zhao, Sree Gongala, Jessie E. P. Sun, David W. Jordan, Chris A. Flask, Mark A. Griswold, Dan Ma, Chaitra Badve   +8 more
wiley   +1 more source

Comparison of Fibrillin-1 and Fibrillin-2 Gene Expression Level in Esophageal Squamous Cell Carcinoma Tumor Tissue and Tumor Margin Tissue. [PDF]

Iran J Med Sci
Mahdizadeh M, Saghaeian Jazi M, Mir SM, Jafari SM.   +3 more
europepmc   +1 more source

Impact of timing on mucosal healing during restaging endoscopy in pediatric Crohn's disease: A retrospective cohort study

JPGN Reports, EarlyView.
Abstract While endoscopic remission is an important target in pediatric Crohn's disease (CD), no consensus for restaging timing exists. This retrospective cohort study assessed the timing and impact of restaging endoscopy in children with new CD in remission, comparing earlier ( ≤ 9 months) versus later endoscopy.
Anna Janecek, Alexandra S. Hudson, David L. Suskind, Hengqi B. Zheng, Samuel Simpson, Dale Lee, Ghassan Wahbeh, Hannibal Person   +7 more
wiley   +1 more source

Superficial Esophageal Cancer Completely Cured With Radiotherapy Alone: A Case Report. [PDF]

Korean J Helicobacter Up Gastrointest Res
Bae HJ, Choe Y, Kim BW.
europepmc   +1 more source

Impact of Environmental and Seasonal Factors on Spontaneous Pneumomediastinum With and Without Pneumorrhachis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Spontaneous pneumomediastinum (SPM) with pneumorrhachis is rare but generally benign and self‐limiting. However, the impact of environmental and seasonal factors on SPM remains unclear. This study investigated their association with SPM onset and clinical outcomes.
Yu‐Wei Liu, Chieh‐Ni Kao, Chi‐Chang Ho, Shah‐Hwa Chou, Pau‐Chung Chen, Shu‐Hung Huang   +5 more
wiley   +1 more source

Endoscopic Ultrasound (EUS)-Based Multimodal Diagnosis of a Rare Intramural Esophageal Squamous Cell Carcinoma: Case Report and Literature Review. [PDF]

J Clin Med
Fanizza J, Mandarino FV, Barchi A, Altieri G, Rosati R, Elmore U, Battaglia S, Facciorusso A, Fuccio L, Donatelli G, Finocchiaro D, Ponzoni M, Danese S, Dell'Anna G.   +13 more
europepmc   +1 more source

Prognostic Factors Impacting Surgical Resection Outcomes in Elderly Patients With Brain Metastasis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Brain metastases (BM) among elderly patients with cancer are increasing, and decision‐making for treatment is complicated by comorbidities. This study aimed to identify prognostic factors that can help make informed decisions regarding surgical resection in elderly patients with BM.
Yu Chang, Heng‐Juei Hsu, Chia‐En Wong, Junmin Song, Kuo‐Chang Huang, Liang‐Chao Wang, Chih‐Hao Tien, Chih‐Yuan Huang, Po‐Hsuan Lee, Chi‐Chen Huang, Jung‐Shun Lee   +10 more
wiley   +1 more source

A mediastinal eosinophilic adenoma misdiagnosed as an esophageal stromal tumor: A case report. [PDF]

J Cardiothorac Surg
Chen S, Wang J, Ao N, Di S, Wu H, Gong T.   +5 more
europepmc   +1 more source