Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
ABSTRACT African Americans have the highest colorectal cancer (CRC) mortality rates in the United States. We performed the first genome‐wide association study (GWAS) of overall and CRC‐specific mortality among African Americans with incident CRC to identify genetic contributors to CRC outcomes.
Thomas Lawler +7 more
wiley +1 more source
Conservative Management of a Rare Gastrobronchial Fistula Following Minimally Invasive Esophagectomy: A Case Report. [PDF]
Chaudhuri U +4 more
europepmc +1 more source
Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley +1 more source
Malignant pleural effusion due to metastatic squamous cell carcinoma exhibiting pseudoglandular and signet ring-like features: a case report. [PDF]
Yu Q, Yang Z.
europepmc +1 more source
Circular RNAs: Epigenetic Puppeteers Pulling the Strings of Cancer Pathogenesis
ABSTRACT Circular RNAs (circRNAs), a unique class of endogenous noncoding RNAs characterized by their covalently closed loop structure, have emerged as pivotal players in cancer biology due to their exceptional stability, tissue‐specific expression, and diverse regulatory functions.
Yimao Wu +4 more
wiley +1 more source
A rare case report of esophageal neuroendocrine carcinoma mimicking a submucosal tumor: Diagnosis confirmed by endoscopic ultrasound-guided fine-needle aspiration. [PDF]
Hu C, Zhu D, Li P, Ye X, Chen Z.
europepmc +1 more source
This comprehensive analysis of gastrointestinal (GI) cancer risk reveals that globally, one in 46 people will develop and one in 73 will die from GI cancers during working age (15–64 years), with 2021 incidence and mortality risks of 2.19% and 1.37%, respectively. Key findings demonstrate striking gender disparities, with males facing nearly double the
Yiming Song +14 more
wiley +1 more source
The gastrin-releasing peptide receptor as a potential biomarker for squamous cell carcinoma. [PDF]
Olguins DB +9 more
europepmc +1 more source

