Results 111 to 120 of about 384,835 (330)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Esophageal Perforation due to Transesophageal Echocardiogram: New Endoscopic Clip Treatment

Case Reports in Gastroenterology, 2014
Esophageal perforation due to transesophageal echocardiogram (TEE) during cardiac surgery is rare. A 72-year-old female underwent TEE during an operation for aortic valve replacement. Further, the patient presented hematemesis.
John Robotis, Andreas Karabinis
doaj   +1 more source

Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments

The FEBS Journal, EarlyView.
Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis, Nadine Gehle, Katia Cosentino   +2 more
wiley   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang, Theng Yi Tay, Simon Gibbs, Ola Niewiadomski   +3 more
wiley   +1 more source

Extrahepatic complications of liver transplantation. [PDF]

, 1985
The massive surgical assault associated with hepatic transplantation makes a high frequency of complications almost inevitable. In this review of 225 patient records, selected at random from cases of liver transplantation in Pittsburgh over a 2 1/2 year ...
Shaw, BW, Starzl, TE, Wood, RP
core   +1 more source

Minimizing Atrioesophageal Fistula Risk After AF Ablation: Risk Factors, Prevention, and Emerging Mini‐Thermal Technology

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Atrial esophageal fistula (AEF) is a rare but life‐threatening complication of atrial fibrillation (AF) ablation, linked to thermal injuries by conventional radiofrequency (RF) and cryo‐balloon (CB) ablation techniques. AEF risk can be mitigated by considering several measures such as tailored power settings of ablation technique, mechanical ...
Muhammed Ibrahim Erbay, Esedullah Yağlı, Tasha Phillips‐Wilson, Arda Çeviker, Henry D. Huang, Joseph E. Marine, Kıvanç Yalın   +6 more
wiley   +1 more source

Ligamentum arteriosum calcification mimicking esophageal perforation: A case report

Journal of Pediatric Surgery Case Reports
Introduction: The ligamentum arteriosum is a structure that connects the pulmonary artery to the aorta in the developing fetus. After birth it usually undergoes fibrous degenerative changes and calcification. Ligamentum arteriosum calcification (LAC) can
Abdulmalek Alzahrani, Mohammed Alsayed, Khalid Nassibi, Ali A. Alzahrani, Samira Alturkistany   +4 more
doaj   +1 more source

Advances in imaging chest tuberculosis: blurring of differences between children and adults [PDF]

, 2009
This article reviews the ongoing role of imaging in the diagnosis of tuberculosis (TB) and its complications. A modern imaging classification of TB, taking into account both adults and children and the blurring of differences in the presentation patterns,
Ahmad, Al-Nasser, Andronikou, Andronikou, Andronikou, Andronikou, Andronikou, Bosch-Marcet, Bosch-Marcet, Buckingham, Burrill, Casas, Conces, De Backer, De Backer, De Villiers, den Boon, du Plessis, Erlank, Erlank, Fraser, Glicklich, Goodman, Goussard, Griffith-Richards, Grobbelaar, Gulati, Hamilton, Haramati, Hartman, Hopewell, Im, Jeong, Kim, Kim, Lee, Lee, Leung, Lighter, Marais, Maydell, Moon, Morris, Nakanishi, Neufang, Perlman, Raviglione, Reid, Rodriguez, Santelli, Scheepers, Stead, Swingler, Theron, Van Dyck, Van Rie, Vanhoenacker, Verver, Verver, Wall, Westcott, Woodring, Yilmaz, Zellweger   +63 more
core   +2 more sources

Pulse Field Ablation for Persistent Atrial Fibrillation: Targeting the Persistent Superior Vena Cava

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Persistent left superior vena cava (PLSVC) is a rare vascular anomaly that can act as a trigger for atrial fibrillation (AF). Thermal ablation in this region carries a notable risk. Pulse field ablation (PFA), a non‐thermal modality, offers a safer alternative.
Sara Vázquez‐Calvo, Vladimir Poletaev, Atul Verma, Vidal Essebag   +3 more
wiley   +1 more source

Management, Prognosis and Early Mortality of Patients with Esophageal Perforation

İstanbul Medical Journal
Introduction: The diagnosis, treatment, and follow-up of 19 patients diagnosed with esophageal perforation in our hospital were evaluated against the current literature.
Enver Reyhan, Habip Sarı, Hilmi Bozkurt, Kübra Şahin, Zekiye Nur Harput, Mehmet Kasım Aydın, Hakan Canbaz   +6 more
doaj   +1 more source