Results 91 to 100 of about 60,843 (278)

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

open access: yesVIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding   +10 more
wiley   +1 more source

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

open access: yesVIEW, EarlyView.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

Diagnostic value of fasting hypopharyngeal salivary pepsin concentration test for laryngopharyngeal reflux disease

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the diagnostic value of the fasting hypopharyngeal salivary pepsin concentration test for laryngopharyngeal reflux disease (LPRD). Methods Volunteers were grouped by reflux symptom index scale, reflux finding score scale, and 24‐h hypopharyngeal‐esophageal multichannel intraluminal impedance with pH monitoring results.
Chao‐Feng Liu   +6 more
wiley   +1 more source

Laryngopharyngeal Reflux: The Impact of Obesity

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This article provides an overview of gastro‐esophageal (GERD) and laryngopharynegal (LPRD) reflux diseases in the context of obesity as a confounding entity. A detailed review of the clinical presentation, pathogenesis, diagnosis, and treatment of laryngopharyngeal reflux disease may be found elsewhere.
Abdul Latif H. Hamdan   +2 more
wiley   +1 more source

Relationship between nasolaryngoscopic findings and pH probe esophageal monitoring in children with clinical manifestations of extra-esophageal reflux

open access: yesInternational Archives of Otorhinolaryngology, 2009
Introduction: The gastroesophageal reflux diagnosis, mainly in patients with atypical manifestations, has been receiving increasing importance. Objective: To relate the nasolaryngoscopic findings with prolonged pH probe esophageal monitoring in children ...
Oliveira, Neide Fatima Cordeiro Diniz   +1 more
doaj  

Management of Vocal Fold Leukoplakia

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
wiley   +1 more source

PROLONGED GASTROESOPHAGEAL REFLUX MONITORING BY IMPEDANCE-PHMETRY: A REVIEW OF THE SUBJECT PONDERED WITH OUR EXPERIENCE WITH 1,200 CASES

open access: yesArquivos de Gastroenterologia, 2018
BACKGROUND: Prolonged monitoring increased our knowledge on gastroesophageal reflux (GER), and the disease became known as gastroesophageal reflux disease (GERD). Prolonged reflux monitoring permits the diagnosis of GERD when endoscopic findings are not
Ary NASI   +2 more
doaj   +1 more source

Combined Transcriptomic and Proteomic Forecast Analyses for Potential Biomarkers of Smoking‐Induced Benign and Malignant Transformation of Vocal Fold Lesions

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Laryngeal dysplasia and Reinke's edema (RE) are common vocal fold lesions associated with smoking. While the former is cancer prone, most cases of the latter do not undergo malignant transformation. Therefore, we proposed identifying biomarkers of smoking‐induced benign‐malignant transformation of vocal fold lesions.
Yun‐Yi Liu, Pei‐Yun Zhuang
wiley   +1 more source

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