Results 51 to 60 of about 60,843 (278)

Inferring respiratory and circulatory parameters from electrical impedance tomography with deep recurrent models [PDF]

arXiv, 2020
Electrical impedance tomography (EIT) is a noninvasive imaging modality that allows a continuous assessment of changes in regional bioimpedance of different organs. One of its most common biomedical applications is monitoring regional ventilation distribution in critically ill patients treated in intensive care units.
arxiv  

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source

Comorbid disorders of esophagus in patients with irritable bowel disease

SVU - International Journal of Medical Sciences
Background: Irritable bowel syndrome(IBS) ,Gastroesophageal reflux disease and functional ooesophageal disorders may overlap and share the same pathophysiologic mechanisms.
Hossam Mahmoud Aabdelwahab*, Bishoy Shehata , Nabila Faiek Amin Mousa   +2 more
doaj   +1 more source

Benchmarking for Public Health Surveillance tasks on Social Media with a Domain-Specific Pretrained Language Model [PDF]

arXiv, 2022
A user-generated text on social media enables health workers to keep track of information, identify possible outbreaks, forecast disease trends, monitor emergency cases, and ascertain disease awareness and response to official health correspondence. This exchange of health information on social media has been regarded as an attempt to enhance public ...
arxiv  

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

Advanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu, Jingjun He, Haoxuan Ying, Cuiying Chen, Chongyang Zheng, Peng Luo, Weiliang Zhu, Ting Wei, Bufu Tang, Jian Zhang   +9 more
wiley   +1 more source

Current Status of Translational Research on Gastroesophageal Reflux Disease

The Korean Journal of Gastroenterology, 2016
The prevalence of gastroesophageal reflux disease (GERD) and the incidence of some of its complications have risen strikingly over the last few decades.
In Du Jeong, Moo In Park
doaj   +1 more source

Two-photon polymerization of optical microresonators for precise pH sensing [PDF]

Light: Advanced Manufacturing (2024)5:54
In water monitoring, environmental analysis, cell culture stability, and biomedical applications, precise pH control is demanded. Traditional methods like pH strips and meters have limitations: pH strips lack precision, while electrochemical meters, though more accurate, are fragile, prone to drift, and unsuitable for small volumes.
arxiv   +1 more source

A fully resolved active musculo-mechanical model for esophageal transport [PDF]

Journal of Computational Physics, Volume 298, 1 October 2015, Pages 446-465, 2015
Esophageal transport is a physiological process that mechanically transports an ingested food bolus from the pharynx to the stomach via the esophagus, a multi-layered muscular tube. This process involves interactions between the bolus, the esophagus, and the neurally coordinated activation of the esophageal muscles.
arxiv   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Normal 24-hour Ambulatory Esophageal pH Values in Koreans

Gut and Liver, 2008
Background/Aims: Twenty-four-hour ambulatory esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease.
doaj   +1 more source