Results 61 to 70 of about 34,431 (291)

Esophageal Acid Exposure in Healthy Adults in Taiwan: Experience with pH Step-up Method by Dual-Channel pH-metry

open access: yesKaohsiung Journal of Medical Sciences, 2005
Esophageal acid exposure is common in normal subjects. The aim of this study was to investigate proximal and distal esophageal acid exposure in asymptomatic volunteers using dual-channel esophageal pH-metry with probe positioning by pH step-up.
Chih-Hsun Yi   +3 more
doaj   +1 more source

Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]

open access: yes, 2011
Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.
Beecher   +41 more
core   +1 more source

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong   +9 more
wiley   +1 more source

Gastroesophageal Reflux in Neurologically Impaired Children: What Are the Risk Factors?

open access: yesGut and Liver, 2017
Background/AimsNeurologically impaired patients frequently suffer from gastrointestinal tract problems, such as gastroesophageal reflux disease (GERD).
Seung Kim, Hong Koh, Joon Soo Lee
doaj   +1 more source

Nonerosive reflux disease :comparative analysis of symptoms severity, endoscopic and 24-hours ph-impedance [PDF]

open access: yes, 2015
Background : Non--‐erosive reflux disease (NERD) has emerged as a real entity in the spectrum of gastroesophageal reflux disease (GERD) and may, indeed, represent the most common manifestation of reflux disease.
Nordin, Noorlina
core  

LINX®, a novel treatment for patients with refractory asthma complicated by gastroesophageal reflux disease: a case report. [PDF]

open access: yes, 2016
BackgroundGastroesophageal reflux disease is one of the most common comorbidities in patients with asthma. Gastroesophageal reflux disease can be linked to difficult-to-control asthma.
Kenyon, Nicholas J   +6 more
core   +2 more sources

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan   +8 more
wiley   +1 more source

Current Status of Translational Research on Gastroesophageal Reflux Disease

open access: yesThe Korean Journal of Gastroenterology, 2016
The prevalence of gastroesophageal reflux disease (GERD) and the incidence of some of its complications have risen strikingly over the last few decades.
In Du Jeong, Moo In Park
doaj   +1 more source

A system-on-chip digital pH meter for use in a wireless diagnostic capsule [PDF]

open access: yes, 2005
This paper describes the design and implementation of a system-on-chip digital pH meter, for use in a wireless capsule application. The system is organized around an 8-bit microcontroller, designed to be functionally identical to the Motorola 6805.
Ali, D., Cumming, D.R.S., Hammond, P.A.
core   +1 more source

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

open access: yesAdvanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen   +15 more
wiley   +1 more source

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